A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis.

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Bibliographic Details
Title: A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis.
Authors: Patel NG; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States., Drakaki A; Department of Medical Biochemistry, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Valummel F; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States., Moore JC; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States., Basu A; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States., Hu B; Massey Cancer Center, Virginia Commonwealth University; Richmond, VA, United States., Dong X; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States., Zhao P; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States., Botman M; Department of Medical Biochemistry, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Spector E; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States., Mochel MC; Department of Pathology, Virginia Commonwealth University; Richmond, VA, United States., Wells L; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States., Koblinski JE; Massey Cancer Center, Virginia Commonwealth University; Richmond, VA, United States.; Department of Pathology, Virginia Commonwealth University; Richmond, VA, United States., Hoeksema MA; Department of Medical Biochemistry, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Weiss RJ; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 22. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.01.21.700969