Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.
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| Title: | Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells. |
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| Authors: | Tan YQ; Guangdong Provincial/Zhuhai Key Laboratory of IRADS & Programme of Food Science and Techonology, Beijing Normal-Hong Kong Baptist University, Zhuhai 519087, China., Shih CL; Clinical Research Center, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City 60002, Taiwan., Chen YC; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan., Lee SH; School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan; Institute of Biopharmaceutical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan., Yang JR; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704302, Taiwan., Kuo CY; Institute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien 97004, Taiwan., Chiou YS; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan. Electronic address: chiouyishiou@kmu.edu.tw. |
| Source: | Journal of hazardous materials [J Hazard Mater] 2026 Feb 15; Vol. 504, pp. 141290. Date of Electronic Publication: 2026 Jan 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41650594 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tan+YQ%22">Tan YQ</searchLink>; Guangdong Provincial/Zhuhai Key Laboratory of IRADS & Programme of Food Science and Techonology, Beijing Normal-Hong Kong Baptist University, Zhuhai 519087, China.<br /><searchLink fieldCode="AU" term="%22Shih+CL%22">Shih CL</searchLink>; Clinical Research Center, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City 60002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan; Institute of Biopharmaceutical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+JR%22">Yang JR</searchLink>; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704302, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+CY%22">Kuo CY</searchLink>; Institute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien 97004, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiou+YS%22">Chiou YS</searchLink>; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan. Electronic address: chiouyishiou@kmu.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229422688%22">Journal of hazardous materials</searchLink> [J Hazard Mater] 2026 Feb 15; Vol. 504, pp. 141290. <i>Date of Electronic Publication: </i>2026 Jan 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9422688 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-3336 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043894%22">03043894 </searchLink><i>NLM ISO Abbreviation: </i>J Hazard Mater <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41650594 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jhazmat.2026.141290 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 141290 Titles: – TitleFull: Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tan YQ – PersonEntity: Name: NameFull: Shih CL – PersonEntity: Name: NameFull: Chen YC – PersonEntity: Name: NameFull: Lee SH – PersonEntity: Name: NameFull: Yang JR – PersonEntity: Name: NameFull: Kuo CY – PersonEntity: Name: NameFull: Chiou YS IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 02 Text: 2026 Feb 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1873-3336 Numbering: – Type: volume Value: 504 Titles: – TitleFull: Journal of hazardous materials Type: main |
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