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Paclitaxel plus cetuximab for the treatment of R/M SCCHN after first-line pembrolizumab failure: primary analysis from the PaceAce trial.

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Title: Paclitaxel plus cetuximab for the treatment of R/M SCCHN after first-line pembrolizumab failure: primary analysis from the PaceAce trial.
Authors: Fuereder T; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria. Electronic address: thorsten.fuereder@meduniwien.ac.at., Klinghammer K; Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Hahn D; Department of Hematology, Oncology, Stem-Cell Transplantation and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany., Grünberger B; Department of Medicine III, Hematology and Medical Oncology, Universitätsklinikum Wiener Neustadt, Wiener Neustadt, Austria., Melchardt T; III(rd) Medical Department, Paracelsus Medical University, Cancer Center, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria., Greil R; III(rd) Medical Department, Paracelsus Medical University, Cancer Center, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria., Kocher F; Department of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Innsbruck, Austria., Gamerith G; Department of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Innsbruck, Austria., Wagner C; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria., Berchtold L; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria; Center for Medical Data Science, Institute of Medical Statistics, Medical University of Vienna, Vienna, Austria., Burian M; Department of ORL, Head and Neck Surgery, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria., Strobl A; Department of ORL, Head and Neck Surgery, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
Source: ESMO open [ESMO Open] 2026 Feb; Vol. 11 (2), pp. 106061. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101690685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7029 (Electronic) Linking ISSN: 20597029 NLM ISO Abbreviation: ESMO Open Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Fuereder+T%22">Fuereder T</searchLink>; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria. Electronic address: thorsten.fuereder@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Klinghammer+K%22">Klinghammer K</searchLink>; Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hahn+D%22">Hahn D</searchLink>; Department of Hematology, Oncology, Stem-Cell Transplantation and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Grünberger+B%22">Grünberger B</searchLink>; Department of Medicine III, Hematology and Medical Oncology, Universitätsklinikum Wiener Neustadt, Wiener Neustadt, Austria.<br /><searchLink fieldCode="AU" term="%22Melchardt+T%22">Melchardt T</searchLink>; III(rd) Medical Department, Paracelsus Medical University, Cancer Center, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Greil+R%22">Greil R</searchLink>; III(rd) Medical Department, Paracelsus Medical University, Cancer Center, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Kocher+F%22">Kocher F</searchLink>; Department of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Gamerith+G%22">Gamerith G</searchLink>; Department of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Wagner+C%22">Wagner C</searchLink>; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Berchtold+L%22">Berchtold L</searchLink>; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria; Center for Medical Data Science, Institute of Medical Statistics, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Burian+M%22">Burian M</searchLink>; Department of ORL, Head and Neck Surgery, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.<br /><searchLink fieldCode="AU" term="%22Strobl+A%22">Strobl A</searchLink>; Department of ORL, Head and Neck Surgery, Ordensklinikum Linz, Barmherzige Schwestern, Linz, Austria.
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  Data: <searchLink fieldCode="JN" term="%22101690685%22">ESMO open</searchLink> [ESMO Open] 2026 Feb; Vol. 11 (2), pp. 106061. <i>Date of Electronic Publication: </i>2026 Feb 05.
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