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CAR-T cells co-expressing IL-7 and CCL19 promote epitope spreading to enhance antitumor immunity.

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Title: CAR-T cells co-expressing IL-7 and CCL19 promote epitope spreading to enhance antitumor immunity.
Authors: Adachi K; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan. fairkid@yamaguchi-u.ac.jp.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan. fairkid@yamaguchi-u.ac.jp., Sakoda Y; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan., Kaisho T; Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.; Industry-Government-Academia Collaboration Promotion Headquarters, Wakayama Medical University, Wakayama, Japan., Tamada K; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan. ktamada@yamaguchi-u.ac.jp.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan. ktamada@yamaguchi-u.ac.jp.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Feb 07; Vol. 75 (3), pp. 68. Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CAR-T cells co-expressing IL-7 and CCL19 promote epitope spreading to enhance antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Adachi+K%22">Adachi K</searchLink>; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan. fairkid@yamaguchi-u.ac.jp.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan. fairkid@yamaguchi-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Sakoda+Y%22">Sakoda Y</searchLink>; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Kaisho+T%22">Kaisho T</searchLink>; Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.; Industry-Government-Academia Collaboration Promotion Headquarters, Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tamada+K%22">Tamada K</searchLink>; Department of Immunology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan. ktamada@yamaguchi-u.ac.jp.; Division of Advanced Cell Therapy, The Research Institute for Cell Design Medical Science, Yamaguchi University, Yamaguchi, Japan. ktamada@yamaguchi-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2026 Feb 07; Vol. 75 (3), pp. 68. <i>Date of Electronic Publication: </i>2026 Feb 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00262-026-04316-z
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      – TitleFull: CAR-T cells co-expressing IL-7 and CCL19 promote epitope spreading to enhance antitumor immunity.
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              Text: 2026 Feb 07
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