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Antioxidant and anti-aging activities of Salvia miltiorrhiza Bunge callus extracts in H2O2-induced premature senescence and chronological aging models of human dermal fibroblasts.

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Title: Antioxidant and anti-aging activities of Salvia miltiorrhiza Bunge callus extracts in H2O2-induced premature senescence and chronological aging models of human dermal fibroblasts.
Authors: Lin SZ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Lin TK; Department of Dermatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan., Kuo WW; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung, Taiwan.; School of Pharmacy, China Medical University, Taichung, Taiwan., Kao SW; Department of Orthopedic Surgery, Chung-Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Kuo CH; Laboratory of Exercise Biochemistry, Department of Health and Physical Education, The Education University of Hong Kong, Hong Kong SAR, China.; School of Physical Education and Sports Science, Soochow University, Suzhou, China.; Department of Movement Sciences and Sports Training, School of Sport Sciences, University of Jordan, Amman, Jordan., Hsieh DJ; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan., Lin YM; Department of Pathology, Changhua Christian Hospital, Changhua, Taiwan., Ho TJ; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Ng SC; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan. shangchuan_622@hotmail.com.; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. shangchuan_622@hotmail.com., Huang CY; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. cyhuang@mail.cmu.edu.tw.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.; Department of Biotechnology, Asia University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.
Source: Biogerontology [Biogerontology] 2026 Feb 07; Vol. 27 (2), pp. 54. Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 100930043 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6768 (Electronic) Linking ISSN: 13895729 NLM ISO Abbreviation: Biogerontology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antioxidant and anti-aging activities of Salvia miltiorrhiza Bunge callus extracts in H<subscript>2</subscript>O<subscript>2</subscript>-induced premature senescence and chronological aging models of human dermal fibroblasts.
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  Data: <searchLink fieldCode="AU" term="%22Lin+SZ%22">Lin SZ</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+TK%22">Lin TK</searchLink>; Department of Dermatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+WW%22">Kuo WW</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung, Taiwan.; School of Pharmacy, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kao+SW%22">Kao SW</searchLink>; Department of Orthopedic Surgery, Chung-Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+CH%22">Kuo CH</searchLink>; Laboratory of Exercise Biochemistry, Department of Health and Physical Education, The Education University of Hong Kong, Hong Kong SAR, China.; School of Physical Education and Sports Science, Soochow University, Suzhou, China.; Department of Movement Sciences and Sports Training, School of Sport Sciences, University of Jordan, Amman, Jordan.<br /><searchLink fieldCode="AU" term="%22Hsieh+DJ%22">Hsieh DJ</searchLink>; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YM%22">Lin YM</searchLink>; Department of Pathology, Changhua Christian Hospital, Changhua, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+TJ%22">Ho TJ</searchLink>; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ng+SC%22">Ng SC</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan. shangchuan_622@hotmail.com.; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. shangchuan_622@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. cyhuang@mail.cmu.edu.tw.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.; Department of Biotechnology, Asia University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan. cyhuang@mail.cmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22100930043%22">Biogerontology</searchLink> [Biogerontology] 2026 Feb 07; Vol. 27 (2), pp. 54. <i>Date of Electronic Publication: </i>2026 Feb 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100930043 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-6768 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213895729%22">13895729 </searchLink><i>NLM ISO Abbreviation: </i>Biogerontology <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10522-025-10381-1
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      – Code: eng
        Text: English
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        StartPage: 54
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      – TitleFull: Antioxidant and anti-aging activities of Salvia miltiorrhiza Bunge callus extracts in H2O2-induced premature senescence and chronological aging models of human dermal fibroblasts.
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            – D: 07
              M: 02
              Text: 2026 Feb 07
              Type: published
              Y: 2026
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