Peripheral Blood Epigenetic Age Acceleration is Associated With Psychosis in Female APOE4 Carriers With Mild Cognitive Impairment and Alzheimer's Disease: A Pilot Study.

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Title: Peripheral Blood Epigenetic Age Acceleration is Associated With Psychosis in Female APOE4 Carriers With Mild Cognitive Impairment and Alzheimer's Disease: A Pilot Study.
Authors: Kwan D; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada., Rashidi-Ranjbar N; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada., Marinas JE; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Namasivayam A; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Churchill N; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada., Fornazzari LR; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Faculty of Medicine, Department of Neurology, University of Toronto, Toronto, ON, Canada., Ismail Z; Cumming School of Medicine, Department of Psychiatry, University of Calgary, Calgary, AB, Canada.; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada., DeLuca V; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada., Schweizer TA; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Munoz DG; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, Division of Pathology, St. Michael's Hospital, Toronto, ON, Canada., Fischer CE; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.
Corporate Authors: Alzheimer’s Disease Neuroimaging Initiative
Source: Journal of geriatric psychiatry and neurology [J Geriatr Psychiatry Neurol] 2026 Feb 07, pp. 8919887261424535. Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 8805645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5708 (Electronic) Linking ISSN: 08919887 NLM ISO Abbreviation: J Geriatr Psychiatry Neurol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kwan+D%22">Kwan D</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rashidi-Ranjbar+N%22">Rashidi-Ranjbar N</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Marinas+JE%22">Marinas JE</searchLink>; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Namasivayam+A%22">Namasivayam A</searchLink>; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Churchill+N%22">Churchill N</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fornazzari+LR%22">Fornazzari LR</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Faculty of Medicine, Department of Neurology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ismail+Z%22">Ismail Z</searchLink>; Cumming School of Medicine, Department of Psychiatry, University of Calgary, Calgary, AB, Canada.; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22DeLuca+V%22">DeLuca V</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Schweizer+TA%22">Schweizer TA</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Munoz+DG%22">Munoz DG</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, Division of Pathology, St. Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fischer+CE%22">Fischer CE</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.; Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.
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      – TitleFull: Peripheral Blood Epigenetic Age Acceleration is Associated With Psychosis in Female APOE4 Carriers With Mild Cognitive Impairment and Alzheimer's Disease: A Pilot Study.
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              Text: 2026 Feb 07
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