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Susceptibility to systemic autoimmunity rather than the presence of the HLA-DR4 peptide binding domain alone leads to severe inflammatory arthritis following inhalation of crystalline silica.

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Bibliographic Details
Title: Susceptibility to systemic autoimmunity rather than the presence of the HLA-DR4 peptide binding domain alone leads to severe inflammatory arthritis following inhalation of crystalline silica.
Authors: Janssen LMF; Department of Immunology and Microbiology, Scripps Research, La Jolla, San Diego, CA, USA.; Department of Public Health and Primary Care, Environment & Health Unit, KU Leuven, Leuven, Belgium., de Ocampo C; Department of Immunology and Microbiology, Scripps Research, La Jolla, San Diego, CA, USA., Kono DH; Department of Immunology and Microbiology, Scripps Research, La Jolla, San Diego, CA, USA., Ronsmans S; Department of Public Health and Primary Care, Environment & Health Unit, KU Leuven, Leuven, Belgium., Ghosh M; Department of Public Health and Primary Care, Environment & Health Unit, KU Leuven, Leuven, Belgium., Hoet PHM; Department of Public Health and Primary Care, Environment & Health Unit, KU Leuven, Leuven, Belgium., Pollard KM; Department of Immunology and Microbiology, Scripps Research, La Jolla, San Diego, CA, USA. mpollard@scripps.edu., Mayeux JM; Department of Immunology and Microbiology, Scripps Research, La Jolla, San Diego, CA, USA. jmayeux@scripps.edu.
Source: Particle and fibre toxicology [Part Fibre Toxicol] 2026 Feb 09; Vol. 23 (1). Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101236354 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-8977 (Electronic) Linking ISSN: 17438977 NLM ISO Abbreviation: Part Fibre Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1743-8977
DOI:10.1186/s12989-026-00662-z