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Ex vivo HNSCC clinical studies using saliva and antiviral or antibacterial chewing gums reveal reduction in carcinogenic microbes.

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Title: Ex vivo HNSCC clinical studies using saliva and antiviral or antibacterial chewing gums reveal reduction in carcinogenic microbes.
Authors: Daniell H; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. hdaniell@upenn.edu.; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, 547 Levy Building, Philadelphia, PA, 19104-6030, USA. hdaniell@upenn.edu., Wakade G; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Singh R; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Nair S; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Basak SK; Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, USA., Srivatsan ES; The Molecular Biology Institute, Los Angeles, USA.; Department of Head and Neck Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, 90073, USA., Bur AM; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Thomas SM; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Wang MB; Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, USA.; Department of Head and Neck Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, 90073, USA.
Source: Scientific reports [Sci Rep] 2026 Feb 09; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Daniell+H%22">Daniell H</searchLink>; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. hdaniell@upenn.edu.; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, 547 Levy Building, Philadelphia, PA, 19104-6030, USA. hdaniell@upenn.edu.<br /><searchLink fieldCode="AU" term="%22Wakade+G%22">Wakade G</searchLink>; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Singh+R%22">Singh R</searchLink>; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Nair+S%22">Nair S</searchLink>; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Basak+SK%22">Basak SK</searchLink>; Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Srivatsan+ES%22">Srivatsan ES</searchLink>; The Molecular Biology Institute, Los Angeles, USA.; Department of Head and Neck Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, 90073, USA.<br /><searchLink fieldCode="AU" term="%22Bur+AM%22">Bur AM</searchLink>; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, KS, 66160, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+SM%22">Thomas SM</searchLink>; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, KS, 66160, USA.<br /><searchLink fieldCode="AU" term="%22Wang+MB%22">Wang MB</searchLink>; Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, USA.; Department of Head and Neck Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, 90073, USA.
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        Value: 10.1038/s41598-026-39062-w
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              Text: 2026 Feb 09
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