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Differential downstream signaling in microglia lacking Alzheimer's-related TREM2 or its adaptor TYROBP/DAP12.

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Title: Differential downstream signaling in microglia lacking Alzheimer's-related TREM2 or its adaptor TYROBP/DAP12.
Authors: Farias Quipildor GE; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA., Belfiore R; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Present Address: Duchenne Regulatory Science Consortium, Critical Path Institute, 1840 East River Road, Suite 100, Tucson, AZ 85718 USA., Althobaiti K; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA., Najarzadeh Z; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697 USA., Glabe C; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697 USA., Readhead BP; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ USA., Gandy S; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; James J Peters VA Medical Center, Bronx, NY 10468 USA., Salton SRJ; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA., Ehrlich ME; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
Source: Molecular neurodegeneration advances [Mol Neurodegener Adv] 2026; Vol. 2 (1), pp. 8. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9919054337306676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3059-4944 (Electronic) Linking ISSN: 30594944 NLM ISO Abbreviation: Mol Neurodegener Adv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Differential downstream signaling in microglia lacking Alzheimer's-related TREM2 or its adaptor TYROBP/DAP12.
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  Data: <searchLink fieldCode="AU" term="%22Farias+Quipildor+GE%22">Farias Quipildor GE</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.<br /><searchLink fieldCode="AU" term="%22Belfiore+R%22">Belfiore R</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Present Address: Duchenne Regulatory Science Consortium, Critical Path Institute, 1840 East River Road, Suite 100, Tucson, AZ 85718 USA.<br /><searchLink fieldCode="AU" term="%22Althobaiti+K%22">Althobaiti K</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.<br /><searchLink fieldCode="AU" term="%22Najarzadeh+Z%22">Najarzadeh Z</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697 USA.<br /><searchLink fieldCode="AU" term="%22Glabe+C%22">Glabe C</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697 USA.<br /><searchLink fieldCode="AU" term="%22Readhead+BP%22">Readhead BP</searchLink>; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ USA.<br /><searchLink fieldCode="AU" term="%22Gandy+S%22">Gandy S</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; James J Peters VA Medical Center, Bronx, NY 10468 USA.<br /><searchLink fieldCode="AU" term="%22Salton+SRJ%22">Salton SRJ</searchLink>; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.<br /><searchLink fieldCode="AU" term="%22Ehrlich+ME%22">Ehrlich ME</searchLink>; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
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  Data: <searchLink fieldCode="JN" term="%229919054337306676%22">Molecular neurodegeneration advances</searchLink> [Mol Neurodegener Adv] 2026; Vol. 2 (1), pp. 8. <i>Date of Electronic Publication: </i>2026 Jan 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9919054337306676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>3059-4944 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2230594944%22">30594944 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurodegener Adv <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026
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