Clinical implications of plasma EGFR T790M and ctDNA shedding across metastatic sites in plasma- or tissue-confirmed EGFR-mutant non-small cell lung cancer treated with lazertinib: a prospective multicenter cohort study.

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Title: Clinical implications of plasma EGFR T790M and ctDNA shedding across metastatic sites in plasma- or tissue-confirmed EGFR-mutant non-small cell lung cancer treated with lazertinib: a prospective multicenter cohort study.
Authors: Kim MJ; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Jung J; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Ji W; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Choi CM; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kim SJ; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Cho HJ; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Hwang YG; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Kim EY; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee SY; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Yoo SS; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Choi S; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Oh IJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea., Kim YC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea., Park CK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea., Yoon SH; Department of Internal Medicine, Pusan National University School of Medicine and Yangsan Hospital, Yangsan, Republic of Korea., Kim YS; Department of Internal Medicine, Pusan National University School of Medicine and Yangsan Hospital, Yangsan, Republic of Korea., Kim MH; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea., Lee MK; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea., Eom JS; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea., Kim SH; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea., Lee JE; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Chung C; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Yeo CD; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee SH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee JC; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Source: Translational lung cancer research [Transl Lung Cancer Res] 2026 Jan 31; Vol. 15 (1), pp. 13. Date of Electronic Publication: 2026 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: Pioneer Bioscience Publishing Company Country of Publication: China NLM ID: 101646875 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2218-6751 (Print) Linking ISSN: 22186751 NLM ISO Abbreviation: Transl Lung Cancer Res Subsets: PubMed not MEDLINE
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  Data: Clinical implications of plasma EGFR T790M and ctDNA shedding across metastatic sites in plasma- or tissue-confirmed EGFR-mutant non-small cell lung cancer treated with lazertinib: a prospective multicenter cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Kim+MJ%22">Kim MJ</searchLink>; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+J%22">Jung J</searchLink>; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ji+W%22">Ji W</searchLink>; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+CM%22">Choi CM</searchLink>; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SJ%22">Kim SJ</searchLink>; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+HJ%22">Cho HJ</searchLink>; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+YG%22">Hwang YG</searchLink>; Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+EY%22">Kim EY</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SY%22">Lee SY</searchLink>; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+SS%22">Yoo SS</searchLink>; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+IJ%22">Oh IJ</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YC%22">Kim YC</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+CK%22">Park CK</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+SH%22">Yoon SH</searchLink>; Department of Internal Medicine, Pusan National University School of Medicine and Yangsan Hospital, Yangsan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YS%22">Kim YS</searchLink>; Department of Internal Medicine, Pusan National University School of Medicine and Yangsan Hospital, Yangsan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MH%22">Kim MH</searchLink>; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MK%22">Lee MK</searchLink>; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Eom+JS%22">Eom JS</searchLink>; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+C%22">Chung C</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yeo+CD%22">Yeo CD</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JC%22">Lee JC</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101646875%22">Translational lung cancer research</searchLink> [Transl Lung Cancer Res] 2026 Jan 31; Vol. 15 (1), pp. 13. <i>Date of Electronic Publication: </i>2026 Jan 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pioneer+Bioscience+Publishing+Company%22">Pioneer Bioscience Publishing Company </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101646875 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2218-6751 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222186751%22">22186751 </searchLink><i>NLM ISO Abbreviation: </i>Transl Lung Cancer Res <i>Subsets: </i>PubMed not MEDLINE
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