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Enhanced lysosomal glycogen breakdown is associated with liver tumorigenesis in glycogen storage disease type III.

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Title: Enhanced lysosomal glycogen breakdown is associated with liver tumorigenesis in glycogen storage disease type III.
Authors: Montalvo-Romeral V; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France., Jauze L; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France.; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Perrot G; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Amaouche M; Université de Lille, CHU Lille, Institut Pasteur de Lille, INSERM, UMR-1011 - EGID, 59000, Lille, France.; Université de Lille, CHU Lille, INSERM UMR-S1172, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, 59000, Lille, France., Gardin A; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France., Aguilar González A; Généthon, 91000 Evry, France., Leblond A; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Zitoun-Ardon C; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Evrard F; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Cosette J; Généthon, 91000 Evry, France., Tatout C; Université Clermont Auvergne, CNRS, INSERM, iGReD Clermont-Ferrand, France.; Université Claude Bernard Lyon 1, SFR Santé Lyon Est, CNRS UAR3453, INSERM US7, Villeurbanne, 69100, France., Bordier F; Généthon, 91000 Evry, France., Bertil-Froidevaux E; Généthon, 91000 Evry, France., Georger C; Généthon, 91000 Evry, France., van Wittenberghe L; Généthon, 91000 Evry, France., Paradis V; INSERM UMR1149, Université Paris Cité, Paris, France.; Service d'Anatomie et de Cytologie Pathologiques Hôpital Beaujon, AP-HP 92110, Clichy, France., Gay S; Université de Tours, 37000, Tours France; Internal Medicine Department Tours Hospital, 37000 Tours, France., Dujardin F; Pathological Department Tours Hospital, 37000 Tours, France., Maillot F; Université de Tours, 37000, Tours France; Internal Medicine Department Tours Hospital, 37000 Tours, France.; UMR INSERM 1253, «iBraiN», 37000 Tours, France., Gautier-Stein A; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Mithieux G; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France., Malfatti E; Reference Center for Neuromuscular Disorders, AP-HP, Henri Mondor University Hospital, 94010, Créteil, France.; Université Paris-Est Créteil, INSERM, UMR-955, IMRB, 94010, Créteil, France., Mussini C; Université Paris-Saclay, AP-HP, Hôpital Bicêtre, Département de Pathologie, 94270, Le Kremlin Bicêtre, France., Labrune P; Université Paris-Saclay, AP-HP, Hôpital Antoine-Béclère, Centre de référence des maladies héréditaires du métabolisme hépatique, Filière G2M, 92140, France., Mayeuf-Louchart A; Université de Lille, CHU Lille, Institut Pasteur de Lille, INSERM, UMR-1011 - EGID, 59000, Lille, France.; Université de Lille, CHU Lille, INSERM UMR-S1172, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, 59000, Lille, France., Ronzitti G; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France., Rajas F; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.
Source: JHEP reports : innovation in hepatology [JHEP Rep] 2025 Dec 02; Vol. 8 (3), pp. 101702. Date of Electronic Publication: 2025 Dec 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: In Process
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  Data: Enhanced lysosomal glycogen breakdown is associated with liver tumorigenesis in glycogen storage disease type III.
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  Data: <searchLink fieldCode="AU" term="%22Montalvo-Romeral+V%22">Montalvo-Romeral V</searchLink>; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Jauze+L%22">Jauze L</searchLink>; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France.; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Perrot+G%22">Perrot G</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Amaouche+M%22">Amaouche M</searchLink>; Université de Lille, CHU Lille, Institut Pasteur de Lille, INSERM, UMR-1011 - EGID, 59000, Lille, France.; Université de Lille, CHU Lille, INSERM UMR-S1172, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Gardin+A%22">Gardin A</searchLink>; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Aguilar+González+A%22">Aguilar González A</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Leblond+A%22">Leblond A</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Zitoun-Ardon+C%22">Zitoun-Ardon C</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Evrard+F%22">Evrard F</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Cosette+J%22">Cosette J</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Tatout+C%22">Tatout C</searchLink>; Université Clermont Auvergne, CNRS, INSERM, iGReD Clermont-Ferrand, France.; Université Claude Bernard Lyon 1, SFR Santé Lyon Est, CNRS UAR3453, INSERM US7, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Bordier+F%22">Bordier F</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Bertil-Froidevaux+E%22">Bertil-Froidevaux E</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Georger+C%22">Georger C</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22van+Wittenberghe+L%22">van Wittenberghe L</searchLink>; Généthon, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Paradis+V%22">Paradis V</searchLink>; INSERM UMR1149, Université Paris Cité, Paris, France.; Service d'Anatomie et de Cytologie Pathologiques Hôpital Beaujon, AP-HP 92110, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Gay+S%22">Gay S</searchLink>; Université de Tours, 37000, Tours France; Internal Medicine Department Tours Hospital, 37000 Tours, France.<br /><searchLink fieldCode="AU" term="%22Dujardin+F%22">Dujardin F</searchLink>; Pathological Department Tours Hospital, 37000 Tours, France.<br /><searchLink fieldCode="AU" term="%22Maillot+F%22">Maillot F</searchLink>; Université de Tours, 37000, Tours France; Internal Medicine Department Tours Hospital, 37000 Tours, France.; UMR INSERM 1253, «iBraiN», 37000 Tours, France.<br /><searchLink fieldCode="AU" term="%22Gautier-Stein+A%22">Gautier-Stein A</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Mithieux+G%22">Mithieux G</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.<br /><searchLink fieldCode="AU" term="%22Malfatti+E%22">Malfatti E</searchLink>; Reference Center for Neuromuscular Disorders, AP-HP, Henri Mondor University Hospital, 94010, Créteil, France.; Université Paris-Est Créteil, INSERM, UMR-955, IMRB, 94010, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Mussini+C%22">Mussini C</searchLink>; Université Paris-Saclay, AP-HP, Hôpital Bicêtre, Département de Pathologie, 94270, Le Kremlin Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Labrune+P%22">Labrune P</searchLink>; Université Paris-Saclay, AP-HP, Hôpital Antoine-Béclère, Centre de référence des maladies héréditaires du métabolisme hépatique, Filière G2M, 92140, France.<br /><searchLink fieldCode="AU" term="%22Mayeuf-Louchart+A%22">Mayeuf-Louchart A</searchLink>; Université de Lille, CHU Lille, Institut Pasteur de Lille, INSERM, UMR-1011 - EGID, 59000, Lille, France.; Université de Lille, CHU Lille, INSERM UMR-S1172, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Ronzitti+G%22">Ronzitti G</searchLink>; Généthon, 91000 Evry, France.; Université Paris-Saclay, Université Evry, INSERM, Integrate Research Unit UMR_S951, 91000 Evry, France.<br /><searchLink fieldCode="AU" term="%22Rajas+F%22">Rajas F</searchLink>; Université Claude Bernard Lyon 1, INSERM, UMR_S1213, Lyon Hepatology Institute-IHU EVEREST, Villeurbanne, 69100, France.
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  Data: <searchLink fieldCode="JN" term="%22101761237%22">JHEP reports : innovation in hepatology</searchLink> [JHEP Rep] 2025 Dec 02; Vol. 8 (3), pp. 101702. <i>Date of Electronic Publication: </i>2025 Dec 02 (<i>Print Publication: </i>2026).
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