Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine Diagnostics.

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Title: Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine Diagnostics.
Authors: Panajotov J; German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Giersch K; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Pflüger LS; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Nörz D; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Grunwald M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Tang HT; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Kaiser M; TIB-Molbiol Syntheselabor GmbH, Berlin., Pischke S; Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany., Ulrich RG; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.; Friedrich-Loeffler-Institut (FLI), Institute of Novel and Emerging Infectious Diseases, Greifswald-Insel Riems, Germany., Pfefferle S; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Schulze Zur Wisch J; Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany., Corman VM; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), associated partner site Charité, Berlin, Germany.; Labor Berlin-Charité Vivantes, Berlin, Germany., Aepfelbacher M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Johne R; German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Lütgehetmann M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.
Source: Journal of medical virology [J Med Virol] 2026 Feb; Vol. 98 (2), pp. e70824.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine Diagnostics.
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  Data: <searchLink fieldCode="AU" term="%22Panajotov+J%22">Panajotov J</searchLink>; German Federal Institute for Risk Assessment (BfR), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Giersch+K%22">Giersch K</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pflüger+LS%22">Pflüger LS</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nörz+D%22">Nörz D</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Grunwald+M%22">Grunwald M</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Tang+HT%22">Tang HT</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kaiser+M%22">Kaiser M</searchLink>; TIB-Molbiol Syntheselabor GmbH, Berlin.<br /><searchLink fieldCode="AU" term="%22Pischke+S%22">Pischke S</searchLink>; Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.<br /><searchLink fieldCode="AU" term="%22Ulrich+RG%22">Ulrich RG</searchLink>; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.; Friedrich-Loeffler-Institut (FLI), Institute of Novel and Emerging Infectious Diseases, Greifswald-Insel Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Pfefferle+S%22">Pfefferle S</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+Zur+Wisch+J%22">Schulze Zur Wisch J</searchLink>; Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.<br /><searchLink fieldCode="AU" term="%22Corman+VM%22">Corman VM</searchLink>; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), associated partner site Charité, Berlin, Germany.; Labor Berlin-Charité Vivantes, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Aepfelbacher+M%22">Aepfelbacher M</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Johne+R%22">Johne R</searchLink>; German Federal Institute for Risk Assessment (BfR), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lütgehetmann+M%22">Lütgehetmann M</searchLink>; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems site, Germany.
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              Text: 2026 Feb
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