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Outcome after Selective early treatment for Closure of patent ductus ARteriosus in preterm babies, a multicentre, masked, randomised placebo-controlled parallel group trial (Baby-OSCAR trial).

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Title: Outcome after Selective early treatment for Closure of patent ductus ARteriosus in preterm babies, a multicentre, masked, randomised placebo-controlled parallel group trial (Baby-OSCAR trial).
Authors: Gupta S; Division of Neonatology, Sidra Medicine, Doha, Qatar.; Department of Engineering, Durham University, Durham, UK., Subhedar NV; Liverpool Women's NHS Foundation Trust, Liverpool, UK., Bell JL; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Bowler U; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Clarke C; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Cole C; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Dempster K; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Edwards C; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Field D; Department of Population Health Sciences, University of Leicester, George Davies Centre, Leicester, UK., Greenaway J; South Tees Hospitals NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK., Hutchison E; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Jamieson N; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Johnson S; Department of Population Health Sciences, University of Leicester, George Davies Centre, Leicester, UK., Kelsell W; NICU, Rosie Hospital, Cambridge University Hospital Foundation Trust, Cambridge, UK., Kennedy A; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., King A; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Laube M; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Linsell L; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Murray D; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., O'Connor H; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Okeke Ogwulu C; Institute of Applied Health Research, University of Birmingham, Birmingham, UK., Pepperell J; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Roberts T; Institute of Applied Health Research, University of Birmingham, Birmingham, UK., Roehr C; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Sinha S; South Tees Hospitals NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK., Stanbury K; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Sutton J; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Welsh R; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Wiles J; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Wyllie J; South Tees Hospitals NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK., Juszczak E; Nottingham Clinical Trials Unit, School of Medicine, University of Nottingham, University Park Nottingham, Nottingham, UK., Hardy P; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Corporate Authors: Baby-OSCAR Collaborative Group
Source: Health technology assessment (Winchester, England) [Health Technol Assess] 2026 Feb; Vol. 30 (11), pp. 1-17.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: NIHR Journals Library Country of Publication: England NLM ID: 9706284 Publication Model: Print Cited Medium: Internet ISSN: 2046-4924 (Electronic) Linking ISSN: 13665278 NLM ISO Abbreviation: Health Technol Assess Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Outcome after Selective early treatment for Closure of patent ductus ARteriosus in preterm babies, a multicentre, masked, randomised placebo-controlled parallel group trial (Baby-OSCAR trial).
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National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Johnson+S%22">Johnson S</searchLink>; Department of Population Health Sciences, University of Leicester, George Davies Centre, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Kelsell+W%22">Kelsell W</searchLink>; NICU, Rosie Hospital, Cambridge University Hospital Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kennedy+A%22">Kennedy A</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22King+A%22">King A</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Laube+M%22">Laube M</searchLink>; 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National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Roberts+T%22">Roberts T</searchLink>; Institute of Applied Health Research, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Roehr+C%22">Roehr C</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink>; South Tees Hospitals NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK.<br /><searchLink fieldCode="AU" term="%22Stanbury+K%22">Stanbury K</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sutton+J%22">Sutton J</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Welsh+R%22">Welsh R</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wiles+J%22">Wiles J</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wyllie+J%22">Wyllie J</searchLink>; South Tees Hospitals NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK.<br /><searchLink fieldCode="AU" term="%22Juszczak+E%22">Juszczak E</searchLink>; Nottingham Clinical Trials Unit, School of Medicine, University of Nottingham, University Park Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Hardy+P%22">Hardy P</searchLink>; National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
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