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A c-Cbl/Cbl-b antagonist inhibits EGFR ubiquitylation and sustains EGFR phosphorylation to enhance corneal re-epithelialization.

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Title: A c-Cbl/Cbl-b antagonist inhibits EGFR ubiquitylation and sustains EGFR phosphorylation to enhance corneal re-epithelialization.
Authors: Tarvestad-Laise K; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202., Monsen RC; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., Crotchett BLM; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202., Rush JS; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202., Ganipisetti S; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., Valmon R; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., DeLeeuw L; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., Burlison J; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., Trent JO; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202., Ceresa BP; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202.; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.; Department of Ophthalmology and Vision Sciences, University of Louisville, Louisville, KY 40202.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Feb 17; Vol. 123 (7), pp. e2518857123. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A c-Cbl/Cbl-b antagonist inhibits EGFR ubiquitylation and sustains EGFR phosphorylation to enhance corneal re-epithelialization.
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  Data: <searchLink fieldCode="AU" term="%22Tarvestad-Laise+K%22">Tarvestad-Laise K</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Monsen+RC%22">Monsen RC</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Crotchett+BLM%22">Crotchett BLM</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Rush+JS%22">Rush JS</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Ganipisetti+S%22">Ganipisetti S</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Valmon+R%22">Valmon R</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22DeLeeuw+L%22">DeLeeuw L</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Burlison+J%22">Burlison J</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Trent+JO%22">Trent JO</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.<br /><searchLink fieldCode="AU" term="%22Ceresa+BP%22">Ceresa BP</searchLink>; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202.; Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202.; Department of Ophthalmology and Vision Sciences, University of Louisville, Louisville, KY 40202.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Feb 17; Vol. 123 (7), pp. e2518857123. <i>Date of Electronic Publication: </i>2026 Feb 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 17
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