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MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.

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Title: MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.
Authors: Heger JM; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; Mildred Scheel School of Oncology Aachen Bonn Cologne Düsseldorf and Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Mattlener J; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Kaul H; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Ferdinandus J; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Schneider J; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany., Schleifenbaum JK; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany., Schneider G; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Schaub V; Department II of Internal Medicine, University of Tübingen, Tübingen, Germany., Hänel M; Department III of Internal Medicine, Klinikum Chemnitz, Chemnitz, Germany., Hellmuth JC; Department of Medicine III, Ludwig Maximilian University Hospital Munich, Munich, Germany., Dierlamm J; University Hospital Hamburg-Eppendorf, Hamburg, Germany., Martin S; Department of Hematology and Oncology, Robert Bosch Hospital, Stuttgart, Germany., Mathas S; Hematology, Oncology, and Cancer Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Biology of Malignant Lymphomas, Berlin, Germany.; Experimental and Clinical Research Center, a joint cooperation between Charité and Max Delbrück Center, Berlin, Germany., Meissner J; Hematology, Oncology and Rheumatology, Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Pegtel DM; Cancer Center Amsterdam, Imaging and Biomarkers and Department of Pathology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Zijlstra JM; Department of Hematology, Amsterdam University Medical Center, Cancer Center Amsterdam and HOVON Imaging Working Group, Amsterdam, The Netherlands., Ossowski A; West German Genome Center and Cologne Center for Genomics, Medical Faculty, University of Cologne, Cologne, Germany., Becker K; West German Genome Center and Cologne Center for Genomics, Medical Faculty, University of Cologne, Cologne, Germany., Hallek M; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany., von Tresckow B; German Hodgkin Study Group, Cologne, Germany.; Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, German Cancer Consortium (Partner Site Essen), Essen, Germany.; Cancer Center Cologne Essen-Partner Site Essen, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Borchmann P; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany., Borchmann S; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.; Liqomics GmbH, Cologne, Germany.
Source: Blood [Blood] 2026 May 07; Vol. 147 (19), pp. 2194-2202.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.
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  Data: <searchLink fieldCode="AU" term="%22Heger+JM%22">Heger JM</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; Mildred Scheel School of Oncology Aachen Bonn Cologne Düsseldorf and Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Mattlener+J%22">Mattlener J</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kaul+H%22">Kaul H</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ferdinandus+J%22">Ferdinandus J</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+J%22">Schneider J</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schleifenbaum+JK%22">Schleifenbaum JK</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+G%22">Schneider G</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schaub+V%22">Schaub V</searchLink>; Department II of Internal Medicine, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hänel+M%22">Hänel M</searchLink>; Department III of Internal Medicine, Klinikum Chemnitz, Chemnitz, Germany.<br /><searchLink fieldCode="AU" term="%22Hellmuth+JC%22">Hellmuth JC</searchLink>; Department of Medicine III, Ludwig Maximilian University Hospital Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dierlamm+J%22">Dierlamm J</searchLink>; University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Martin+S%22">Martin S</searchLink>; Department of Hematology and Oncology, Robert Bosch Hospital, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Mathas+S%22">Mathas S</searchLink>; Hematology, Oncology, and Cancer Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Biology of Malignant Lymphomas, Berlin, Germany.; Experimental and Clinical Research Center, a joint cooperation between Charité and Max Delbrück Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Meissner+J%22">Meissner J</searchLink>; Hematology, Oncology and Rheumatology, Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pegtel+DM%22">Pegtel DM</searchLink>; Cancer Center Amsterdam, Imaging and Biomarkers and Department of Pathology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zijlstra+JM%22">Zijlstra JM</searchLink>; Department of Hematology, Amsterdam University Medical Center, Cancer Center Amsterdam and HOVON Imaging Working Group, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ossowski+A%22">Ossowski A</searchLink>; West German Genome Center and Cologne Center for Genomics, Medical Faculty, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+K%22">Becker K</searchLink>; West German Genome Center and Cologne Center for Genomics, Medical Faculty, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Hallek+M%22">Hallek M</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22von+Tresckow+B%22">von Tresckow B</searchLink>; German Hodgkin Study Group, Cologne, Germany.; Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, German Cancer Consortium (Partner Site Essen), Essen, Germany.; Cancer Center Cologne Essen-Partner Site Essen, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Borchmann+P%22">Borchmann P</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Borchmann+S%22">Borchmann S</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.; Cancer Center Cologne Essen-Partner Site Cologne, CIO Cologne, University of Cologne, Cologne, Germany.; Cologne Lymphoma Working Group, Cologne, Germany.; German Hodgkin Study Group, Cologne, Germany.; Liqomics GmbH, Cologne, Germany.
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