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Symptomatic radiation necrosis after concurrent targeted therapy and stereotactic radiosurgery for brain metastases: a bicentric retrospective analysis.

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Title: Symptomatic radiation necrosis after concurrent targeted therapy and stereotactic radiosurgery for brain metastases: a bicentric retrospective analysis.
Authors: Steele EM; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA., Hall JT; Virginia Oncology Associates, Norfolk, VA, USA., Lui K; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA., Darawsheh R; University of California San Francisco School of Medicine, San Francisco, CA, USA., Shumway JW; Department of Radiation Oncology, El Camino Hospital, Mountain View, CA, USA., Carey LA; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Reeder-Hayes KE; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Lee CB; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Moschos SJ; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Collichio FA; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Sengupta S; Department of Neurology, Tufts Medical Center, Boston, MA, USA., Higgins DM; Department of Neurosurgery, University of North Carolina, Chapel Hill, NC, USA., Chaudhary RT; Division of Oncology, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA., Yogendran LV; Department of Neurology, University of Cincinnati, Cincinnati, OH, USA., Struve TD; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA., Vatner RE; Kettering Health Cancer Care, Kettering, OH, USA., Pater LE; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA., Breneman JC; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA., Andaluz NO; Department of Neurosurgery, University of Cincinnati, Cincinnati, OH, USA., Forbes JA; Department of Neurosurgery, University of Cincinnati, Cincinnati, OH, USA., Gupta GP; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA., Weiner AA; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA., Wang K; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA., Shen CJ; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA. colette_shen@med.unc.edu.
Source: Journal of neuro-oncology [J Neurooncol] 2026 Feb 09; Vol. 176 (3), pp. 203. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Symptomatic radiation necrosis after concurrent targeted therapy and stereotactic radiosurgery for brain metastases: a bicentric retrospective analysis.
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  Data: <searchLink fieldCode="AU" term="%22Steele+EM%22">Steele EM</searchLink>; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA.<br /><searchLink fieldCode="AU" term="%22Hall+JT%22">Hall JT</searchLink>; Virginia Oncology Associates, Norfolk, VA, USA.<br /><searchLink fieldCode="AU" term="%22Lui+K%22">Lui K</searchLink>; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Darawsheh+R%22">Darawsheh R</searchLink>; University of California San Francisco School of Medicine, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shumway+JW%22">Shumway JW</searchLink>; Department of Radiation Oncology, El Camino Hospital, Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Carey+LA%22">Carey LA</searchLink>; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Reeder-Hayes+KE%22">Reeder-Hayes KE</searchLink>; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lee+CB%22">Lee CB</searchLink>; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Moschos+SJ%22">Moschos SJ</searchLink>; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Collichio+FA%22">Collichio FA</searchLink>; Division of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sengupta+S%22">Sengupta S</searchLink>; Department of Neurology, Tufts Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Higgins+DM%22">Higgins DM</searchLink>; Department of Neurosurgery, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhary+RT%22">Chaudhary RT</searchLink>; Division of Oncology, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Yogendran+LV%22">Yogendran LV</searchLink>; Department of Neurology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Struve+TD%22">Struve TD</searchLink>; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Vatner+RE%22">Vatner RE</searchLink>; Kettering Health Cancer Care, Kettering, OH, USA.<br /><searchLink fieldCode="AU" term="%22Pater+LE%22">Pater LE</searchLink>; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Breneman+JC%22">Breneman JC</searchLink>; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Andaluz+NO%22">Andaluz NO</searchLink>; Department of Neurosurgery, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Forbes+JA%22">Forbes JA</searchLink>; Department of Neurosurgery, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+GP%22">Gupta GP</searchLink>; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA.<br /><searchLink fieldCode="AU" term="%22Weiner+AA%22">Weiner AA</searchLink>; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA.<br /><searchLink fieldCode="AU" term="%22Wang+K%22">Wang K</searchLink>; Department of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Shen+CJ%22">Shen CJ</searchLink>; Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA. colette_shen@med.unc.edu.
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  Data: <searchLink fieldCode="JN" term="%228309335%22">Journal of neuro-oncology</searchLink> [J Neurooncol] 2026 Feb 09; Vol. 176 (3), pp. 203. <i>Date of Electronic Publication: </i>2026 Feb 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309335 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7373 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220167594X%22">0167594X </searchLink><i>NLM ISO Abbreviation: </i>J Neurooncol <i>Subsets: </i>MEDLINE
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