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Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons.

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Title: Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons.
Authors: Blackburn E; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at UCL, University College London, London, UK.; The Francis Crick Institute, London, UK., Birsa N; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK., Lopes AT; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK., Fisher EMC; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK., Lazo OM; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at UCL, University College London, London, UK.; Facultad de Psicología y Humanidades, Universidad San Sebastián, Santiago, Chile., Schiavo G; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK. giampietro.schiavo@ucl.ac.uk.; UK Dementia Research Institute at UCL, University College London, London, UK. giampietro.schiavo@ucl.ac.uk.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 11; Vol. 17 (1), pp. 214. Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Blackburn+E%22">Blackburn E</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at UCL, University College London, London, UK.; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Birsa+N%22">Birsa N</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Lopes+AT%22">Lopes AT</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Fisher+EMC%22">Fisher EMC</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Lazo+OM%22">Lazo OM</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at UCL, University College London, London, UK.; Facultad de Psicología y Humanidades, Universidad San Sebastián, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Schiavo+G%22">Schiavo G</searchLink>; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK. giampietro.schiavo@ucl.ac.uk.; UK Dementia Research Institute at UCL, University College London, London, UK. giampietro.schiavo@ucl.ac.uk.
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              Text: 2026 Feb 11
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