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Berberine C9-Derivatives Selective Cytotoxicity Depends on Balance Between Mitochondrial Damage and DNA Intercalation.

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Title: Berberine C9-Derivatives Selective Cytotoxicity Depends on Balance Between Mitochondrial Damage and DNA Intercalation.
Authors: Kolchanova AY; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation., Lyamzaev KG; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation., Valutsa N; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation., Gladkova ED; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation., Luzina OA; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation., Ipatova DA; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation., Kartsev VG; InterBioScreen Ltd, Chernogolovka, Russian Federation., Volcho KP; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation., Dontsova OA; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation.; Center of Molecular and Cellular Biology, Moscow, Russian Federation., Skvortsov DA; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.
Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2026 Feb; Vol. 359 (2), pp. e70199.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE
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  Data: Berberine C9-Derivatives Selective Cytotoxicity Depends on Balance Between Mitochondrial Damage and DNA Intercalation.
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  Data: <searchLink fieldCode="AU" term="%22Kolchanova+AY%22">Kolchanova AY</searchLink>; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Lyamzaev+KG%22">Lyamzaev KG</searchLink>; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Valutsa+N%22">Valutsa N</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Gladkova+ED%22">Gladkova ED</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Luzina+OA%22">Luzina OA</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Ipatova+DA%22">Ipatova DA</searchLink>; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Kartsev+VG%22">Kartsev VG</searchLink>; InterBioScreen Ltd, Chernogolovka, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Volcho+KP%22">Volcho KP</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Salakhutdinov+NF%22">Salakhutdinov NF</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the SB of RAS, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Dontsova+OA%22">Dontsova OA</searchLink>; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation.; Center of Molecular and Cellular Biology, Moscow, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Skvortsov+DA%22">Skvortsov DA</searchLink>; Chemistry Department and AN Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russian Federation.
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              Text: 2026 Feb
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