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Case report: A case of mast cell leukemia treated with avapritinib: from diagnostic challenge to transplantation.

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Title: Case report: A case of mast cell leukemia treated with avapritinib: from diagnostic challenge to transplantation.
Authors: Faraci DG; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy., Caravelli D; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy., Schianca FC; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy., Zaniol E; Collection and Processing Laboratory, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy., Enrico F; Hospital Pharmacy, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy., Boffano C; Radiology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy., Labate C; SC Neurologia, Ospedale Civile Edoardo Agnelli Di Pinerolo, Pinerolo, Italy., Sterpi G; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Department of Medical Sciences, University of Turin, Turin, Italy., Fornari A; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Department of Oncology, Division of Pathology, San Luigi Gonzaga Hospital, Turin, Italy., Sangiorgio V; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Division of Hematology U, University Hospital A.O.U. 'Città della Salute e della Scienza', University of Turin, Torino, Italy., Crisà E; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.
Source: Frontiers in oncology [Front Oncol] 2026 Jan 26; Vol. 16, pp. 1746589. Date of Electronic Publication: 2026 Jan 26 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Case report: A case of mast cell leukemia treated with avapritinib: from diagnostic challenge to transplantation.
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  Data: <searchLink fieldCode="AU" term="%22Faraci+DG%22">Faraci DG</searchLink>; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Caravelli+D%22">Caravelli D</searchLink>; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Schianca+FC%22">Schianca FC</searchLink>; Medical Oncology, Hematopoietic Stem Cells Unit, Turin Metropolitan Transplant Center, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Zaniol+E%22">Zaniol E</searchLink>; Collection and Processing Laboratory, Candiolo Cancer Institute, (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Enrico+F%22">Enrico F</searchLink>; Hospital Pharmacy, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Boffano+C%22">Boffano C</searchLink>; Radiology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Labate+C%22">Labate C</searchLink>; SC Neurologia, Ospedale Civile Edoardo Agnelli Di Pinerolo, Pinerolo, Italy.<br /><searchLink fieldCode="AU" term="%22Sterpi+G%22">Sterpi G</searchLink>; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Department of Medical Sciences, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Fornari+A%22">Fornari A</searchLink>; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Department of Oncology, Division of Pathology, San Luigi Gonzaga Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Sangiorgio+V%22">Sangiorgio V</searchLink>; Pathology Unit, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.; Division of Hematology U, University Hospital A.O.U. 'Città della Salute e della Scienza', University of Turin, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Crisà+E%22">Crisà E</searchLink>; Department of Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia - Istituto di Ricovero e Cura a Carattere Scientifico (FPO-IRCCS), Turin, Italy.
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