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NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026.

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Title: NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026.
Authors: Cheng HH; 1Fred Hutchinson Cancer Center., Giri VN; 2Yale Cancer Center/Smilow Cancer Hospital., Goggins M; 3Johns Hopkins Kimmel Cancer Center., Yurgelun MB; 4Dana-Farber/Brigham and Women's Cancer Center., Karlan BY; 5UCLA Jonsson Comprehensive Cancer Center., Norquist BS; 1Fred Hutchinson Cancer Center., Daly MB; 6Fox Chase Cancer Center., Pal T; 7Vanderbilt-Ingram Cancer Center., AlHilli Z; 8Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute., Arun B; 9The University of Texas MD Anderson Cancer Center., Churpek J; 10University of Wisconsin Carbone Cancer Center., Colonna S; 11Huntsman Cancer Institute at the University of Utah., Domchek SM; 12Abramson Cancer Center at the University of Pennsylvania., Escobar MR; 13O'Neal Comprehensive Cancer Center at UAB., Fejerman L; 14UC Davis Comprehensive Cancer Center., Friedman S; 15FORCE: Facing Our Risk of Cancer Empowered., Hagemann A; 16Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine., Hendrix A; 17St. Jude Children's Research Hospital/The University of Tennessee Health Science Center., Huo D; 18The UChicago Medicine Comprehensive Cancer Center., Hutton ML; 19Roswell Park Comprehensive Cancer Center., Kassem N; 20Indiana University Melvin and Bren Simon Comprehensive Cancer Center., Khan S; 21Robert H. Lurie Comprehensive Cancer Center of Northwestern University., Kurian AW; 22Stanford Cancer Institute., Laronga C; 23Moffitt Cancer Center., Mak JS; 24UCSF Helen Diller Family Comprehensive Cancer Center., Maxwell KN; 12Abramson Cancer Center at the University of Pennsylvania., McDonnell K; 25City of Hope National Medical Center., Merajver SD; 26University of Michigan Rogel Cancer Center., Mersch J; 27UT Southwestern Simmons Comprehensive Cancer Center., Offit K; 28Memorial Sloan Kettering Cancer Center., Plichta J; 29Duke Cancer Institute., Rash D; 30UC San Diego Moores Cancer Center., Reiser G; 31Fred & Pamela Buffett Cancer Center., Senter-Jamieson L; 32The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute., Shannon KM; 33Mass General Cancer Center., Welborn J; 14UC Davis Comprehensive Cancer Center., Wick MJ; 34Mayo Clinic Comprehensive Cancer Center., Wood M; 35University of Colorado Cancer Center., Darlow S; 36National Comprehensive Cancer Network., Diwan Z; 36National Comprehensive Cancer Network., Dwyer M; 36National Comprehensive Cancer Network.
Source: Journal of the National Comprehensive Cancer Network : JNCCN [J Natl Compr Canc Netw] 2026 Feb; Vol. 24 (2), pp. 2-10.
Publication Type: Journal Article; Practice Guideline
Journal Info: Publisher: Harborside Press Country of Publication: United States NLM ID: 101162515 Publication Model: Print Cited Medium: Internet ISSN: 1540-1413 (Electronic) Linking ISSN: 15401405 NLM ISO Abbreviation: J Natl Compr Canc Netw Subsets: MEDLINE
Database: MEDLINE Ultimate
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Lurie Comprehensive Cancer Center of Northwestern University.<br /><searchLink fieldCode="AU" term="%22Kurian+AW%22">Kurian AW</searchLink>; 22Stanford Cancer Institute.<br /><searchLink fieldCode="AU" term="%22Laronga+C%22">Laronga C</searchLink>; 23Moffitt Cancer Center.<br /><searchLink fieldCode="AU" term="%22Mak+JS%22">Mak JS</searchLink>; 24UCSF Helen Diller Family Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Maxwell+KN%22">Maxwell KN</searchLink>; 12Abramson Cancer Center at the University of Pennsylvania.<br /><searchLink fieldCode="AU" term="%22McDonnell+K%22">McDonnell K</searchLink>; 25City of Hope National Medical Center.<br /><searchLink fieldCode="AU" term="%22Merajver+SD%22">Merajver SD</searchLink>; 26University of Michigan Rogel Cancer Center.<br /><searchLink fieldCode="AU" term="%22Mersch+J%22">Mersch J</searchLink>; 27UT Southwestern Simmons Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Offit+K%22">Offit K</searchLink>; 28Memorial Sloan Kettering Cancer Center.<br /><searchLink fieldCode="AU" term="%22Plichta+J%22">Plichta J</searchLink>; 29Duke Cancer Institute.<br /><searchLink fieldCode="AU" term="%22Rash+D%22">Rash D</searchLink>; 30UC San Diego Moores Cancer Center.<br /><searchLink fieldCode="AU" term="%22Reiser+G%22">Reiser G</searchLink>; 31Fred & Pamela Buffett Cancer Center.<br /><searchLink fieldCode="AU" term="%22Senter-Jamieson+L%22">Senter-Jamieson L</searchLink>; 32The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.<br /><searchLink fieldCode="AU" term="%22Shannon+KM%22">Shannon KM</searchLink>; 33Mass General Cancer Center.<br /><searchLink fieldCode="AU" term="%22Welborn+J%22">Welborn J</searchLink>; 14UC Davis Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Wick+MJ%22">Wick MJ</searchLink>; 34Mayo Clinic Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Wood+M%22">Wood M</searchLink>; 35University of Colorado Cancer Center.<br /><searchLink fieldCode="AU" term="%22Darlow+S%22">Darlow S</searchLink>; 36National Comprehensive Cancer Network.<br /><searchLink fieldCode="AU" term="%22Diwan+Z%22">Diwan Z</searchLink>; 36National Comprehensive Cancer Network.<br /><searchLink fieldCode="AU" term="%22Dwyer+M%22">Dwyer M</searchLink>; 36National Comprehensive Cancer Network.
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              Text: 2026 Feb
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