Efficacy and Safety of Combination Therapy With Low Dose of Telmisartan and S-Amlodipine in Patients With Hypertension: A Randomized, Double-Blind, Multicenter, Therapeutic Confirmatory, Phase III Clinical Trial.
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| Title: | Efficacy and Safety of Combination Therapy With Low Dose of Telmisartan and S-Amlodipine in Patients With Hypertension: A Randomized, Double-Blind, Multicenter, Therapeutic Confirmatory, Phase III Clinical Trial. |
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| Authors: | Lee SH; Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Division of Cardiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, South Korea., Park K; Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, South Korea., Lee KH; Department of Internal Medicine, Chonnam National University Hospital, Gwangju, South Korea., Cho Y; Division of Cardiology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, South Korea., Kim DH; Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Lim S; Division of Cardiology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Bo Yoon S; Department of Cardiology, H-Plus Yangji Hospital, Seoul, South Korea., Jang JS; Division of Cardiology, Dongguk University Ilsan Hospital, Goyang, South Korea., Lim HS; Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea., Doh JH; Department of Cardiology, Inje University Ilsan-Paik Hospital, Goyang, South Korea., Kim DY; Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea., Sohn IS; Department of Cardiology, Kyung Hee University College of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea., Cheon DY; Department of Internal Medicine, Division of Cardiology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, South Korea., Bae MH; Department of Internal Medicine, Kyungpook National University Hospital, Daegu, South Korea., Kim SH; Division of Cardiology, Department of Medicine, Konkuk University Medical Center, Seoul, South Korea., Lee Y; Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri City, Gyeonggi-do, South Korea., Ihm SH; Division of Cardiology, Department of Internal Medicine, Bucheon St. Mary's Hospital and Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Choi RK; Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Mediplex Sejong Hospital, Incheon, South Korea., Park HJ; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea., Pyun WB; Division of Cardiology, Department of Internal Medicine, Ewha Womans University, Seoul, South Korea., Choi S; Department of Cardiololgy, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea., Shin J; Division of Cardiology, Department of Internal Medicine, Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Republic of Korea. Electronic address: jhs2003@hanyang.ac.kr. |
| Source: | Clinical therapeutics [Clin Ther] 2026 Mar; Vol. 48 (3), pp. 240-246. Date of Electronic Publication: 2026 Feb 10. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III |
| Journal Info: | Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41672793 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and Safety of Combination Therapy With Low Dose of Telmisartan and S-Amlodipine in Patients With Hypertension: A Randomized, Double-Blind, Multicenter, Therapeutic Confirmatory, Phase III Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Division of Cardiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+K%22">Park K</searchLink>; Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Department of Internal Medicine, Chonnam National University Hospital, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Cho+Y%22">Cho Y</searchLink>; Division of Cardiology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DH%22">Kim DH</searchLink>; Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lim+S%22">Lim S</searchLink>; Division of Cardiology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Bo+Yoon+S%22">Bo Yoon S</searchLink>; Department of Cardiology, H-Plus Yangji Hospital, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Jang+JS%22">Jang JS</searchLink>; Division of Cardiology, Dongguk University Ilsan Hospital, Goyang, South Korea.<br /><searchLink fieldCode="AU" term="%22Lim+HS%22">Lim HS</searchLink>; Department of Cardiology, Ajou University School of Medicine, Suwon, South Korea.<br /><searchLink fieldCode="AU" term="%22Doh+JH%22">Doh JH</searchLink>; Department of Cardiology, Inje University Ilsan-Paik Hospital, Goyang, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DY%22">Kim DY</searchLink>; Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+IS%22">Sohn IS</searchLink>; Department of Cardiology, Kyung Hee University College of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Cheon+DY%22">Cheon DY</searchLink>; Department of Internal Medicine, Division of Cardiology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, South Korea.<br /><searchLink fieldCode="AU" term="%22Bae+MH%22">Bae MH</searchLink>; Department of Internal Medicine, Kyungpook National University Hospital, Daegu, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Division of Cardiology, Department of Medicine, Konkuk University Medical Center, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri City, Gyeonggi-do, South Korea.<br /><searchLink fieldCode="AU" term="%22Ihm+SH%22">Ihm SH</searchLink>; Division of Cardiology, Department of Internal Medicine, Bucheon St. Mary's Hospital and Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Choi+RK%22">Choi RK</searchLink>; Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Mediplex Sejong Hospital, Incheon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+HJ%22">Park HJ</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Pyun+WB%22">Pyun WB</searchLink>; Division of Cardiology, Department of Internal Medicine, Ewha Womans University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; Department of Cardiololgy, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Shin+J%22">Shin J</searchLink>; Division of Cardiology, Department of Internal Medicine, Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Republic of Korea. Electronic address: jhs2003@hanyang.ac.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227706726%22">Clinical therapeutics</searchLink> [Clin Ther] 2026 Mar; Vol. 48 (3), pp. 240-246. <i>Date of Electronic Publication: </i>2026 Feb 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Excerpta+Medica%22">Excerpta Medica </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7706726 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-114X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201492918%22">01492918 </searchLink><i>NLM ISO Abbreviation: </i>Clin Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41672793 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.clinthera.2026.01.001 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 240 Titles: – TitleFull: Efficacy and Safety of Combination Therapy With Low Dose of Telmisartan and S-Amlodipine in Patients With Hypertension: A Randomized, Double-Blind, Multicenter, Therapeutic Confirmatory, Phase III Clinical Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lee SH – PersonEntity: Name: NameFull: Park K – PersonEntity: Name: NameFull: Lee KH – PersonEntity: Name: NameFull: Cho Y – PersonEntity: Name: NameFull: Kim DH – PersonEntity: Name: NameFull: Lim S – PersonEntity: Name: NameFull: Bo Yoon S – PersonEntity: Name: NameFull: Jang JS – PersonEntity: Name: NameFull: Lim HS – PersonEntity: Name: NameFull: Doh JH – PersonEntity: Name: NameFull: Kim DY – PersonEntity: Name: NameFull: Sohn IS – PersonEntity: Name: NameFull: Cheon DY – PersonEntity: Name: NameFull: Bae MH – PersonEntity: Name: NameFull: Kim SH – PersonEntity: Name: NameFull: Lee Y – PersonEntity: Name: NameFull: Ihm SH – PersonEntity: Name: NameFull: Choi RK – PersonEntity: Name: NameFull: Park HJ – PersonEntity: Name: NameFull: Pyun WB – PersonEntity: Name: NameFull: Choi S – PersonEntity: Name: NameFull: Shin J IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1879-114X Numbering: – Type: volume Value: 48 – Type: issue Value: 3 Titles: – TitleFull: Clinical therapeutics Type: main |
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