Prognosis and Treatment Response in Aggressive-variant Prostate Cancer and Treatment-related Neuroendocrine Prostate Cancer: A Systematic Review and Meta-analysis.

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Title: Prognosis and Treatment Response in Aggressive-variant Prostate Cancer and Treatment-related Neuroendocrine Prostate Cancer: A Systematic Review and Meta-analysis.
Authors: Pedrani M; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Salfi G; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Institute of Oncology Research, Bellinzona, Switzerland., Pecoraro G; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy., Puglisi M; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; School of Specialization in Medical Oncology, G. Barresi Department of Human Pathology, University of Messina, Messina, Italy., Turco F; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Tortola L; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Urechie V; Department of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Leone G; Cancer Institute, Department of Oncology, University College London, London, UK; Garvan Institute of Medical Research, Darlinghurst, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia., Lin HM; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Vogl U; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Barizzi J; Laboratory of Genetics and Molecular Pathology, Institute of Pathology, Ente Ospedaliero Cantonale, Locarno, Switzerland., Treglia G; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Cuzzocrea M; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Paone G; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Lai P; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Theurillat JP; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Zilli T; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Department of Radiation Oncology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland., Gillessen S; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Merler S; Oncology Department, San Maurizio Central Hospital, Bolzano, Italy., Pereira Mestre R; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland. Electronic address: ricardo.pereiramestre@eoc.ch.
Source: European urology oncology [Eur Urol Oncol] 2026 Jun; Vol. 9 (3), pp. 673-689. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101724904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2588-9311 (Electronic) Linking ISSN: 25889311 NLM ISO Abbreviation: Eur Urol Oncol Subsets: MEDLINE
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  Data: Prognosis and Treatment Response in Aggressive-variant Prostate Cancer and Treatment-related Neuroendocrine Prostate Cancer: A Systematic Review and Meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Pedrani+M%22">Pedrani M</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Salfi+G%22">Salfi G</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pecoraro+G%22">Pecoraro G</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Puglisi+M%22">Puglisi M</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; School of Specialization in Medical Oncology, G. Barresi Department of Human Pathology, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Turco+F%22">Turco F</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tortola+L%22">Tortola L</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Urechie+V%22">Urechie V</searchLink>; Department of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Leone+G%22">Leone G</searchLink>; Cancer Institute, Department of Oncology, University College London, London, UK; Garvan Institute of Medical Research, Darlinghurst, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Lin+HM%22">Lin HM</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vogl+U%22">Vogl U</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Barizzi+J%22">Barizzi J</searchLink>; Laboratory of Genetics and Molecular Pathology, Institute of Pathology, Ente Ospedaliero Cantonale, Locarno, Switzerland.<br /><searchLink fieldCode="AU" term="%22Treglia+G%22">Treglia G</searchLink>; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cuzzocrea+M%22">Cuzzocrea M</searchLink>; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Paone+G%22">Paone G</searchLink>; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lai+P%22">Lai P</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Theurillat+JP%22">Theurillat JP</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zilli+T%22">Zilli T</searchLink>; Nuclear Medicine Clinic, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Department of Radiation Oncology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gillessen+S%22">Gillessen S</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Merler+S%22">Merler S</searchLink>; Oncology Department, San Maurizio Central Hospital, Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Pereira+Mestre+R%22">Pereira Mestre R</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Institute of Oncology Research, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland. Electronic address: ricardo.pereiramestre@eoc.ch.
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  Data: <searchLink fieldCode="JN" term="%22101724904%22">European urology oncology</searchLink> [Eur Urol Oncol] 2026 Jun; Vol. 9 (3), pp. 673-689. <i>Date of Electronic Publication: </i>2026 Feb 10.
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