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Title: PRIMARY-AI: outcomes-based standards to safeguard primary care in the AI era.
Authors: Zeng D; School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China., Car LT; King's Population Health Institute, King's College London, London, UK.; Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK., Khunti K; University of Leicester, Leicester, UK., Liu Y; School of Health Policy and Management, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Bärnighausen T; Heidelberg Institute of Global Health (HIGH), Medical Faculty and University Hospital, Heidelberg University, Heidelberg, Germany.; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Harvard University, Boston, USA.; Africa Health Research Institute, Somkhele and Durban, Durban, South Africa., Chavannes NH; Department of Public Health and Primary Care, National eHealth Living Lab, Leiden University Medical Center, Leiden, the Netherlands., Keane PA; Institute of Ophthalmology, University College London, London, UK.; Moorfields Eye Hospital NHS Foundation Trust, London, UK.; NIHR Moorfields Biomedical Research Centre, London, UK., Kunz H; Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK.; Institute of Health Informatics, University College of London, London, UK., Xue L; Schwarzman College and School of Public Policy and Management, Tsinghua University, Beijing, China., Sung JJY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Tham YC; Centre for Innovation and Precision Eye Health and Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore., Righetto L; Springer, Milan, Italy., Sarker R; The Lancet Group, London, UK., Wong SYS; Jockey Club School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China., Boudreau D; Institute of Heath Sciences Education, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Dai Q; Department of Automation, Tsinghua University, Beijing, China.; Institute of Brain and Cognitive Sciences, Tsinghua University, Beijing, China.; IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.; Beijing National Research Center for Information Science and Technology, Tsinghua University, Beijing, China., Jia W; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Liu Y; Department of Computer Science and Technology, Tsinghua University, Beijing, China.; Institute for AI Industry Research, Tsinghua University, Beijing, China., Shen D; School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, Shanghai Tech University, Shanghai, China.; Shanghai United Imaging Intelligence Company, Shanghai, China.; Shanghai Clinical Research and Trial Center, Shanghai, China., Liu J; Department of Psychological and Cognitive Sciences, Tsinghua University, Beijing, China., Shen W; School of Law, Tsinghua University, Beijing, China., Ji JS; Vanke School of Public Health, Tsinghua University, Beijing, China., Wang Z; General Practice ACP, Tsinghua University, Beijing, China.; Department of General Practice, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.; General Practice Health Laboratory, Beijing Tsinghua Changgung Hospital, Beijing, China., Wang Z; Department of General Practice, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China., Wang H; First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China., Tang S; Department of Population Health Science, School of Medicine, Duke University, Durham, NC, USA.; Duke Global Health Institute, Duke University, Durham, NC, USA.; Global Health Research Center, Duke Kunshan University, Kunshan, China.; SingHealth-Duke-NUS Global Health Institute, Duke-NUS School of Medicine, Singapore, Singapore., Pei C; School of Health Policy and Management, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; Heidelberg Institute of Global Health (HIGH), Medical Faculty and University Hospital, Heidelberg University, Heidelberg, Germany., Jiang Z; School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China., Zou Z; School of Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China., Qin Y; School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China., Li H; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wang Y; National Engineering Research Center of Software Engineering, Peking University, Beijing, China., Gunasekeran DV; Data Science and Technology, MOH Office for Healthcare Transformation, Singapore, Singapore.; School of Medicine, National University of Singapore, Singapore, Singapore.; Ophthalmology ACP, Duke-NUS Medical School, Singapore, Singapore., Wong S; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Healthcare Group Polyclinics, Singapore, Singapore., Xu D; Acacia Lab for Implementation Science, School of Health Management, Southern Medical University, Guangzhou, China.; Southern Medical University Institute for Global Health, Dermatology Hospital, Southern Medical University, Guangzhou, China.; Center for World Health Organization Studies and Department of Health Management, School of Health Management of Southern Medical University, Guangzhou, China., Urbanowicz R; Cedars Sinai Medical Center, Los Angeles, CA, USA., Laranjo L; Westmead Applied Research Centre, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia., Neves AL; Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK.; RISE-Health, MEDCIDS- Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine of the University of Porto, Porto, Portugal., Liu N; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., He Y; King's College London, London, UK., Le PV; College of Health Sciences, VinUniversity, Hanoi, Vietnam.; School of Medicine, University of California, San Francisco, CA, USA., Bressler N; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Atun R; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Health Policy and Management, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA., Klonoff DC; Mills-Peninsula Medical Center (Sutter Health), San Mateo, CA, USA., Sheng B; Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders, Department of Computer Science and Engineering, School of Electronic, Information, and Electrical Engineering, Institute for Proactive Healthcare, Shanghai Jiao Tong University, Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China.; MOE Key Laboratory of AI, School of Electronic, Information, and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, China., Shah N; Department of Medicine, Stanford School of Medicine, Stanford, CA, USA.; Clinical Excellence Research Center, Stanford School of Medicine, Stanford, CA, USA.; Technology and Digital Solutions, Stanford Health Care, Palo Alto, CA, USA., Car J; King's Population Health Institute, King's College London, London, UK. josip.car@kcl.ac.uk., Wong TY; School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China. ophwty@nus.edu.sg.; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore. ophwty@nus.edu.sg.; Beijing Key Laboratory of Intelligent Diagnostic Technology and Devices for Major Blinding Eye Diseases, Tsinghua Medicine, Tsinghua University, Beijing, China. ophwty@nus.edu.sg.; Beijing Visual Science and Translational Eye Research Institute, Beijing Tsinghua Changgung Hospital Eye Center, Tsinghua Medicine, Tsinghua University, Beijing, China. ophwty@nus.edu.sg.
Source: Nature medicine [Nat Med] 2026 Mar; Vol. 32 (3), pp. 778-781.
Publication Type: Letter
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE; In Process
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            NameFull: Shah N
      – PersonEntity:
          Name:
            NameFull: Car J
      – PersonEntity:
          Name:
            NameFull: Wong TY
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: 2026 Mar
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1546-170X
          Numbering:
            – Type: volume
              Value: 32
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Nature medicine
              Type: main
ResultId 1