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Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3.

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Title: Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3.
Authors: Chen X; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Guo S; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Li YG; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Liu AK; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Kuang J; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Shi P; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China., Yu L; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China. luyuesr@ustc.edu.cn.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China. luyuesr@ustc.edu.cn., Yang F; School of Chemistry and Chemical Engineering, ZhangJiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, 201204, China. f_yang@sjtu.edu.cn., Tian CL; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China. cltian@ustc.edu.cn.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China. cltian@ustc.edu.cn.; School of Chemistry and Chemical Engineering, ZhangJiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, 201204, China. cltian@ustc.edu.cn.; High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230030, China. cltian@ustc.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Jul; Vol. 47 (7), pp. 1980-1989. Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3.
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  Data: <searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Guo+S%22">Guo S</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Li+YG%22">Li YG</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Liu+AK%22">Liu AK</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Kuang+J%22">Kuang J</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Shi+P%22">Shi P</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China. luyuesr@ustc.edu.cn.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China. luyuesr@ustc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+F%22">Yang F</searchLink>; School of Chemistry and Chemical Engineering, ZhangJiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, 201204, China. f_yang@sjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tian+CL%22">Tian CL</searchLink>; School of Life Sciences, Division of Life Sciences and Medicine, Joint Center for Biological Analytical Chemistry, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230026, China. cltian@ustc.edu.cn.; Anhui Engineering Laboratory of Peptide Drug, University of Science and Technology of China, Hefei, 230026, China. cltian@ustc.edu.cn.; School of Chemistry and Chemical Engineering, ZhangJiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai, 201204, China. cltian@ustc.edu.cn.; High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230030, China. cltian@ustc.edu.cn.
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        Value: 10.1038/s41401-025-01740-2
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        Text: English
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        StartPage: 1980
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      – TitleFull: Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3.
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              Text: 2026 Jul
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