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Ultra-high-resolution synchrotron phase-contrast CT enables microstructural pulmonary imaging at clinical dose levels.

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Title: Ultra-high-resolution synchrotron phase-contrast CT enables microstructural pulmonary imaging at clinical dose levels.
Authors: Benke CV; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., Reiser J; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., D'Amico L; School of Physics and Astronomy, Monash University, Clayton, Australia.; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.; European Molecular Biology Laboratory (EMBL), Hamburg Unit c/o DESY, Hamburg, Germany., Sagar MMR; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany., Sodini N; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Dreossi D; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Contillo A; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Longo E; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Prašek M; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Stern S; X-Spectrum GmbH, Hamburg, Germany., Baratella E; Department of Radiology, Hospital of Cattinara, University of Trieste, Trieste, Italy., Cova MA; Department of Radiology, Hospital of Cattinara, University of Trieste, Trieste, Italy., Confalonieri M; Department of Pulmonology, Hospital of Cattinara, University of Trieste, Trieste, Italy.; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Confalonieri P; Department of Pulmonology, Hospital of Cattinara, University of Trieste, Trieste, Italy.; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Zanconati F; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., D'Errico S; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Radaelli D; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Bruscagin T; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Bonazza D; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy., Bayat S; Inserm UA07 STROBE Laboratory, Université Grenoble Alpes, Grenoble, France., Nolte P; Faculty of Engineering and Health, University of Applied Sciences and Arts Goettingen, Goettingen, Germany., Neubert L; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany., Petzold-Mügge C; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany., Werlein C; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany., Knudsen L; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany., Shin HO; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany., Kamp JC; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany., Hosseini ASA; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany., Wagner WL; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Wielpütz MO; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Biederer J; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Faculty of Medicine, Kiel University, Kiel, Germany.; Faculty of Medicine and Life Sciences, University of Latvia, Riga, Latvia., Kauczor HU; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., Alves F; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany.; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany.; Department of Haematology and Medical Oncology, University Medical Center Goettingen, Goettingen, Germany., Tromba G; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy., Dullin C; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany. christian.dullin@med.uni-goettingen.de.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany. christian.dullin@med.uni-goettingen.de.; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy. christian.dullin@med.uni-goettingen.de.; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany. christian.dullin@med.uni-goettingen.de.; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany. christian.dullin@med.uni-goettingen.de.
Source: Respiratory research [Respir Res] 2026 Feb 11; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ultra-high-resolution synchrotron phase-contrast CT enables microstructural pulmonary imaging at clinical dose levels.
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  Data: <searchLink fieldCode="AU" term="%22Benke+CV%22">Benke CV</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reiser+J%22">Reiser J</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22D'Amico+L%22">D'Amico L</searchLink>; School of Physics and Astronomy, Monash University, Clayton, Australia.; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.; European Molecular Biology Laboratory (EMBL), Hamburg Unit c/o DESY, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sagar+MMR%22">Sagar MMR</searchLink>; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sodini+N%22">Sodini N</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Dreossi+D%22">Dreossi D</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Contillo+A%22">Contillo A</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Longo+E%22">Longo E</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Prašek+M%22">Prašek M</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Stern+S%22">Stern S</searchLink>; X-Spectrum GmbH, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Baratella+E%22">Baratella E</searchLink>; Department of Radiology, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Cova+MA%22">Cova MA</searchLink>; Department of Radiology, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Confalonieri+M%22">Confalonieri M</searchLink>; Department of Pulmonology, Hospital of Cattinara, University of Trieste, Trieste, Italy.; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Confalonieri+P%22">Confalonieri P</searchLink>; Department of Pulmonology, Hospital of Cattinara, University of Trieste, Trieste, Italy.; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Zanconati+F%22">Zanconati F</searchLink>; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22D'Errico+S%22">D'Errico S</searchLink>; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Radaelli+D%22">Radaelli D</searchLink>; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Bruscagin+T%22">Bruscagin T</searchLink>; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Bonazza+D%22">Bonazza D</searchLink>; Department of Medical Surgical and Health Sciences, Hospital of Cattinara, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Bayat+S%22">Bayat S</searchLink>; Inserm UA07 STROBE Laboratory, Université Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Nolte+P%22">Nolte P</searchLink>; Faculty of Engineering and Health, University of Applied Sciences and Arts Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Neubert+L%22">Neubert L</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Petzold-Mügge+C%22">Petzold-Mügge C</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Werlein+C%22">Werlein C</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Knudsen+L%22">Knudsen L</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Shin+HO%22">Shin HO</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Kamp+JC%22">Kamp JC</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hosseini+ASA%22">Hosseini ASA</searchLink>; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+WL%22">Wagner WL</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Wielpütz+MO%22">Wielpütz MO</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Biederer+J%22">Biederer J</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Faculty of Medicine, Kiel University, Kiel, Germany.; Faculty of Medicine and Life Sciences, University of Latvia, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Kauczor+HU%22">Kauczor HU</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Alves+F%22">Alves F</searchLink>; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany.; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany.; Department of Haematology and Medical Oncology, University Medical Center Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tromba+G%22">Tromba G</searchLink>; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy.<br /><searchLink fieldCode="AU" term="%22Dullin+C%22">Dullin C</searchLink>; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany. christian.dullin@med.uni-goettingen.de.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany. christian.dullin@med.uni-goettingen.de.; Elettra-Sincrotrone Trieste S.C.p.A, Basovizza, Italy. christian.dullin@med.uni-goettingen.de.; Translational Molecular Imaging, Max-Planck-Institute for Multidisciplinary Sciences, Goettingen, Germany. christian.dullin@med.uni-goettingen.de.; Department of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany. christian.dullin@med.uni-goettingen.de.
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