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DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase.

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Title: DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase.
Authors: Wang Y; Committee on Genetics, Genomics & System Biology, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Li Y; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA., Ye C; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Irkliyenko I; University of California, Berkeley-University of California, San Francisco, USA., Gao L; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Department of Medicine, The University of Chicago, Chicago, IL, USA., Bissonnette M; Department of Medicine, The University of Chicago, Chicago, IL, USA., Dai Q; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Tang W; Department of Chemistry, The University of Chicago, Chicago, IL, USA., He C; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Department of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
Source: Genome biology [Genome Biol] 2026 Feb 11; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Committee on Genetics, Genomics & System Biology, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ye+C%22">Ye C</searchLink>; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Irkliyenko+I%22">Irkliyenko I</searchLink>; University of California, Berkeley-University of California, San Francisco, USA.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bissonnette+M%22">Bissonnette M</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Dai+Q%22">Dai Q</searchLink>; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Tang+W%22">Tang W</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22He+C%22">He C</searchLink>; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Department of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2026 Feb 11; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100960660 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-760X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214747596%22">14747596 </searchLink><i>NLM ISO Abbreviation: </i>Genome Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13059-026-03991-6
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              Text: 2026 Feb 11
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