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A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization.

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Title: A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization.
Authors: Long KD; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Silberger DJ; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA., Hernandez J; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA., Detchemendy T; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA., Moates DB; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA., Abdalla T; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Hastings LE; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Jani A; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Kim J; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Prados M; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Miller MB; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA., Rodriguez JM; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA., Leal SM Jr; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Feb 06. Date of Electronic Publication: 2026 Feb 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization.
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  Data: <searchLink fieldCode="AU" term="%22Long+KD%22">Long KD</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Silberger+DJ%22">Silberger DJ</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+J%22">Hernandez J</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Detchemendy+T%22">Detchemendy T</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Moates+DB%22">Moates DB</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Abdalla+T%22">Abdalla T</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Hastings+LE%22">Hastings LE</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Jani+A%22">Jani A</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Prados+M%22">Prados M</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Miller+MB%22">Miller MB</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+JM%22">Rodriguez JM</searchLink>; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham; Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Leal+SM+Jr%22">Leal SM Jr</searchLink>; Department of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham; Birmingham, AL, USA.; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 Feb 06. <i>Date of Electronic Publication: </i>2026 Feb 06.
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        Value: 10.64898/2026.02.05.25342495
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        Text: English
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              Text: 2026 Feb 06
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