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Phosphatidylcholine biosynthesis pathways in Cryptococcus neoformans: functional interplay and impact on virulence.

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Title: Phosphatidylcholine biosynthesis pathways in Cryptococcus neoformans: functional interplay and impact on virulence.
Authors: Timboni FDS; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil., Garay AV; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.; Laboratory of Molecular Biophysics, University of Brasília, Brasília, Federal District, Brazil., de Castro RJA; Laboratory of Molecular Biophysics, University of Brasília, Brasília, Federal District, Brazil.; Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil., Trindade GB; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University from São Paulo, Ribeirão Preto, São Paulo, Brazil.; Bi-Institutional Translational Medicine Platform, Oswaldo Cruz Foundation (Fiocruz), Ribeirão Preto, São Paulo, Brazil., da Silva NO; Laboratory of Molecular Biology of Pathogenic Fungi, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil., Coelho LC; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil., Dias VM; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil., de Sousa APCV; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil., Del Poeta M; Department of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, United States.; Division of Infectious Diseases, School of Medicine, Stony Brook University, Stony Brook, NY, United States.; Veterans Affairs Medical Center, Northport, NY, United States., Albuquerque P; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Laboratory of Molecular Biology of Pathogenic Fungi, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil., Bocca AL; Bi-Institutional Translational Medicine Platform, Oswaldo Cruz Foundation (Fiocruz), Ribeirão Preto, São Paulo, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; National Institute of Science and Technology in Human Pathogenic Fungi, Ribeirão Preto, São Paulo, Brazil., Fernandes L; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 Jan 27; Vol. 15, pp. 1736171. Date of Electronic Publication: 2026 Jan 27 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phosphatidylcholine biosynthesis pathways in Cryptococcus neoformans: functional interplay and impact on virulence.
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  Data: <searchLink fieldCode="AU" term="%22Timboni+FDS%22">Timboni FDS</searchLink>; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Garay+AV%22">Garay AV</searchLink>; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.; Laboratory of Molecular Biophysics, University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Castro+RJA%22">de Castro RJA</searchLink>; Laboratory of Molecular Biophysics, University of Brasília, Brasília, Federal District, Brazil.; Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Trindade+GB%22">Trindade GB</searchLink>; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University from São Paulo, Ribeirão Preto, São Paulo, Brazil.; Bi-Institutional Translational Medicine Platform, Oswaldo Cruz Foundation (Fiocruz), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+NO%22">da Silva NO</searchLink>; Laboratory of Molecular Biology of Pathogenic Fungi, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Coelho+LC%22">Coelho LC</searchLink>; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Dias+VM%22">Dias VM</searchLink>; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Sousa+APCV%22">de Sousa APCV</searchLink>; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Del+Poeta+M%22">Del Poeta M</searchLink>; Department of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, United States.; Division of Infectious Diseases, School of Medicine, Stony Brook University, Stony Brook, NY, United States.; Veterans Affairs Medical Center, Northport, NY, United States.<br /><searchLink fieldCode="AU" term="%22Albuquerque+P%22">Albuquerque P</searchLink>; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Laboratory of Molecular Biology of Pathogenic Fungi, Institute of Biological Sciences, University of Brasília, Brasília, Federal District, Brazil.; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil.<br /><searchLink fieldCode="AU" term="%22Bocca+AL%22">Bocca AL</searchLink>; Bi-Institutional Translational Medicine Platform, Oswaldo Cruz Foundation (Fiocruz), Ribeirão Preto, São Paulo, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; National Institute of Science and Technology in Human Pathogenic Fungi, Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Fernandes+L%22">Fernandes L</searchLink>; Postgraduate Program of Microbial Biology, University of Brasília, Brasília, Federal District, Brazil.; Center of Molecular Biotechnology (C-BIOTECH), University of Brasília, Brasília, Federal District, Brazil.; Faculty of Health Sciences and Technologies, University of Brasilia, Brasília, Federal District, Brazil.
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