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Metformin Suppresses Glioblastoma Tumor Growth and Progression Through the AMPK/FoxO3a/Survivin Axis.

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Title: Metformin Suppresses Glioblastoma Tumor Growth and Progression Through the AMPK/FoxO3a/Survivin Axis.
Authors: Cavaliere F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Cormace A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Spadafora S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Fava M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Yang SH; Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93 Jungbudaero, Paldal-gu, Suwon 16247, Republic of Korea., Lee JE; Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93 Jungbudaero, Paldal-gu, Suwon 16247, Republic of Korea., Nocito MC; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Sirianni R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Casaburi I; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Garofalo C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 3, 40139 Bologna, Italy., Sisci D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Morelli C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Lanzino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
Source: Cells [Cells] 2026 Feb 06; Vol. 15 (3). Date of Electronic Publication: 2026 Feb 06.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metformin Suppresses Glioblastoma Tumor Growth and Progression Through the AMPK/FoxO3a/Survivin Axis.
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  Data: <searchLink fieldCode="AU" term="%22Cavaliere+F%22">Cavaliere F</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Pellegrino+M%22">Pellegrino M</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Cormace+A%22">Cormace A</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Spadafora+S%22">Spadafora S</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Fava+M%22">Fava M</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Yang+SH%22">Yang SH</searchLink>; Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93 Jungbudaero, Paldal-gu, Suwon 16247, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93 Jungbudaero, Paldal-gu, Suwon 16247, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nocito+MC%22">Nocito MC</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Sirianni+R%22">Sirianni R</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Casaburi+I%22">Casaburi I</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Garofalo+C%22">Garofalo C</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 3, 40139 Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Sisci+D%22">Sisci D</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Morelli+C%22">Morelli C</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Lanzino+M%22">Lanzino M</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101600052%22">Cells</searchLink> [Cells] 2026 Feb 06; Vol. 15 (3). <i>Date of Electronic Publication: </i>2026 Feb 06.
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