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TFR2 p.A75V mutation aggravates liver iron overload in alcoholic liver disease via ERK pathway.

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Title: TFR2 p.A75V mutation aggravates liver iron overload in alcoholic liver disease via ERK pathway.
Authors: Xie C; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Liu Y; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Wang X; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Huang L; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Wang X; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Zhang W; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Wu L; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Liu T; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Wang P; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Liu L; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Fan X; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Jia J; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China., Ou X; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China. ouxj16@126.com.; State Key Laboratory of Digestive Health, Beijing, China. ouxj16@126.com.; National Clinical Research Center of Digestive Disease, Beijing, China. ouxj16@126.com., Xu A; Experimental and Translational Research Center, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, 100050, China. xuanjian1981@sina.com., Cong M; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China. maomao0623@sina.com.; State Key Laboratory of Digestive Health, Beijing, China. maomao0623@sina.com.; National Clinical Research Center of Digestive Disease, Beijing, China. maomao0623@sina.com.
Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2026 Feb 12; Vol. 104 (1), pp. 44. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1440 (Electronic) Linking ISSN: 09462716 NLM ISO Abbreviation: J Mol Med (Berl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TFR2 p.A75V mutation aggravates liver iron overload in alcoholic liver disease via ERK pathway.
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  Data: <searchLink fieldCode="AU" term="%22Xie+C%22">Xie C</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fan+X%22">Fan X</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jia+J%22">Jia J</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China.; State Key Laboratory of Digestive Health, Beijing, China.; National Clinical Research Center of Digestive Disease, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ou+X%22">Ou X</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China. ouxj16@126.com.; State Key Laboratory of Digestive Health, Beijing, China. ouxj16@126.com.; National Clinical Research Center of Digestive Disease, Beijing, China. ouxj16@126.com.<br /><searchLink fieldCode="AU" term="%22Xu+A%22">Xu A</searchLink>; Experimental and Translational Research Center, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, 100050, China. xuanjian1981@sina.com.<br /><searchLink fieldCode="AU" term="%22Cong+M%22">Cong M</searchLink>; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, 95 Yong-an Road, Xicheng District, Beijing, China. maomao0623@sina.com.; State Key Laboratory of Digestive Health, Beijing, China. maomao0623@sina.com.; National Clinical Research Center of Digestive Disease, Beijing, China. maomao0623@sina.com.
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  Data: <searchLink fieldCode="JN" term="%229504370%22">Journal of molecular medicine (Berlin, Germany)</searchLink> [J Mol Med (Berl)] 2026 Feb 12; Vol. 104 (1), pp. 44. <i>Date of Electronic Publication: </i>2026 Feb 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9504370 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1440 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209462716%22">09462716 </searchLink><i>NLM ISO Abbreviation: </i>J Mol Med (Berl) <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00109-026-02640-6
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        Text: English
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