Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats.

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Bibliographic Details
Title: Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats.
Authors: Liu H; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Wang F; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China; Department of Psychiatry, Ningbo Kangning Hospital, Ningbo 315201, Zhejiang, China., Zhang Z; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Huang X; Department of Obstetrics, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315040, China., Chen S; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Wang Y; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Zhou Y; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Wu T; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China., Wu M; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Shi B; School of Psychology and Mental Health, North China University of Science and Technology, Tang'shan 063210, Hebei Province, China., Lai M; Department of Psychiatry, Ningbo Kangning Hospital, Ningbo 315201, Zhejiang, China., Liu H; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China; Department of Psychiatry, Ningbo Kangning Hospital, Ningbo 315201, Zhejiang, China., Zhou W; Department of Psychiatry, The Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China; Department of Psychiatry, Ningbo Kangning Hospital, Ningbo 315201, Zhejiang, China. Electronic address: whzhou@vip.163.com.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 May; Vol. 134, pp. 106481. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
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