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The endoplasmic reticulum stress-regulated XBP1s transcription factor drives a negative feedback loop on FLT3 expression in leukemia cells.

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Title: The endoplasmic reticulum stress-regulated XBP1s transcription factor drives a negative feedback loop on FLT3 expression in leukemia cells.
Authors: Philippe C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: celine.philippe@inserm.fr., Jaud M; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France., Da Cunha C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France., Van Den Berghe L; Vectorology Platform, CRCT Technological Pole, F-31037, Toulouse, France., Farce M; Flow cytometry and cell sorting Platform, CRCT Technological Pole, F-31037, Toulouse, France., Bousquet M; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France., Pyronnet S; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France., Mazzolini L; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: laurent.mazzolini@inserm.fr., Touriol C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: christian.touriol@inserm.fr.
Source: Cancer letters [Cancer Lett] 2026 Apr 10; Vol. 643, pp. 218310. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: The endoplasmic reticulum stress-regulated XBP1s transcription factor drives a negative feedback loop on FLT3 expression in leukemia cells.
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  Data: <searchLink fieldCode="AU" term="%22Philippe+C%22">Philippe C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: celine.philippe@inserm.fr.<br /><searchLink fieldCode="AU" term="%22Jaud+M%22">Jaud M</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Da+Cunha+C%22">Da Cunha C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Van+Den+Berghe+L%22">Van Den Berghe L</searchLink>; Vectorology Platform, CRCT Technological Pole, F-31037, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Farce+M%22">Farce M</searchLink>; Flow cytometry and cell sorting Platform, CRCT Technological Pole, F-31037, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bousquet+M%22">Bousquet M</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Pyronnet+S%22">Pyronnet S</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Mazzolini+L%22">Mazzolini L</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: laurent.mazzolini@inserm.fr.<br /><searchLink fieldCode="AU" term="%22Touriol+C%22">Touriol C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Toulouse, France. Electronic address: christian.touriol@inserm.fr.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 Apr 10; Vol. 643, pp. 218310. <i>Date of Electronic Publication: </i>2026 Feb 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41679424
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        Value: 10.1016/j.canlet.2026.218310
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              Text: 2026 Apr 10
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