Preclinical 203/212Pb-DOTA-Based Pretargeted Radioimmunotherapy in Nude Mice Bearing Established Human Colorectal Cancer Xenografts.

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Title: Preclinical 203/212Pb-DOTA-Based Pretargeted Radioimmunotherapy in Nude Mice Bearing Established Human Colorectal Cancer Xenografts.
Authors: Vaughn BA; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Veach DR; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Weill Cornell Medicine, New York, New York., Vargas DB; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Seo S; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Punzalan B; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Rinne SS; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Fung EK; Department of Medical Physics, Weill Cornell Medicine, New York, New York., Xu H; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Guo HF; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Yang G; Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York; and., Ouerfelli O; Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York; and., Carrasco SE; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine and Rockefeller University, New York, New York., St Jean S; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine and Rockefeller University, New York, New York., Cheung NV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Larson SM; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York., Cheal SM; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York; smc4002@med.cornell.edu.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2026 May 01; Vol. 67 (5), pp. 700-708. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE
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  Data: Preclinical <superscript>203/212</superscript>Pb-DOTA-Based Pretargeted Radioimmunotherapy in Nude Mice Bearing Established Human Colorectal Cancer Xenografts.
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  Data: <searchLink fieldCode="AU" term="%22Vaughn+BA%22">Vaughn BA</searchLink>; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Veach+DR%22">Veach DR</searchLink>; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Vargas+DB%22">Vargas DB</searchLink>; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Seo+S%22">Seo S</searchLink>; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Punzalan+B%22">Punzalan B</searchLink>; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Rinne+SS%22">Rinne SS</searchLink>; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Fung+EK%22">Fung EK</searchLink>; Department of Medical Physics, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Guo+HF%22">Guo HF</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York; and.<br /><searchLink fieldCode="AU" term="%22Ouerfelli+O%22">Ouerfelli O</searchLink>; Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York; and.<br /><searchLink fieldCode="AU" term="%22Carrasco+SE%22">Carrasco SE</searchLink>; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine and Rockefeller University, New York, New York.<br /><searchLink fieldCode="AU" term="%22St+Jean+S%22">St Jean S</searchLink>; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine and Rockefeller University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Cheung+NV%22">Cheung NV</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Larson+SM%22">Larson SM</searchLink>; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Cheal+SM%22">Cheal SM</searchLink>; Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, New York; smc4002@med.cornell.edu.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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      – TitleFull: Preclinical 203/212Pb-DOTA-Based Pretargeted Radioimmunotherapy in Nude Mice Bearing Established Human Colorectal Cancer Xenografts.
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