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Transdermal testosterone gel vs placebo in women with diminished ovarian reserve prior to in vitro fertilization: a randomized, clinical trial.

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Title: Transdermal testosterone gel vs placebo in women with diminished ovarian reserve prior to in vitro fertilization: a randomized, clinical trial.
Authors: Polyzos NP; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain. nikpol@dexeus.com.; Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium. nikpol@dexeus.com., Leathersich SJ; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Martínez F; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain., Blockeel C; Brussels IVF, Centre for Reproductive Medicine, Universitair Ziekenhuis Brussel, Brussels, Belgium., Gosálvez A; Hospital Universitario Quiròn Madrid, Madrid, Spain., de la Fuente L; Hospital Universitario 12 Octubre, Madrid, Spain., Pinborg A; Fertility Clinic, Copenhagen, Rigshospitalet, Denmark., Fàbregues F; Hospital Clínic de Barcelona, Barcelona, Spain., Stoop D; Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium., Rodriguez I; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain., de Geyter C; University Hospital Basel, Basel, Switzerland., Davis SR; Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Endocrinology and Diabetes, Alfred Health, Melbourne, VIC, Australia., Humaidan P; Regional Hospital Skive, Skive, Denmark.
Source: Nature communications [Nat Commun] 2026 Feb 12; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Transdermal testosterone gel vs placebo in women with diminished ovarian reserve prior to in vitro fertilization: a randomized, clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Polyzos+NP%22">Polyzos NP</searchLink>; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain. nikpol@dexeus.com.; Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium. nikpol@dexeus.com.<br /><searchLink fieldCode="AU" term="%22Leathersich+SJ%22">Leathersich SJ</searchLink>; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain.; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martínez+F%22">Martínez F</searchLink>; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blockeel+C%22">Blockeel C</searchLink>; Brussels IVF, Centre for Reproductive Medicine, Universitair Ziekenhuis Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Gosálvez+A%22">Gosálvez A</searchLink>; Hospital Universitario Quiròn Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22de+la+Fuente+L%22">de la Fuente L</searchLink>; Hospital Universitario 12 Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Pinborg+A%22">Pinborg A</searchLink>; Fertility Clinic, Copenhagen, Rigshospitalet, Denmark.<br /><searchLink fieldCode="AU" term="%22Fàbregues+F%22">Fàbregues F</searchLink>; Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Stoop+D%22">Stoop D</searchLink>; Department of Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Rodriguez+I%22">Rodriguez I</searchLink>; Dexeus Fertility, Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Universitari Dexeus, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22de+Geyter+C%22">de Geyter C</searchLink>; University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Davis+SR%22">Davis SR</searchLink>; Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Endocrinology and Diabetes, Alfred Health, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Humaidan+P%22">Humaidan P</searchLink>; Regional Hospital Skive, Skive, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 12; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 12.
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