Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome.
Saved in:
| Title: | Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome. |
|---|---|
| Authors: | Verboven AHA; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Puvogel S; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Latour BL; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Kolsters N; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Lewerissa EI; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Mijdam R; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Dyke E; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Duineveld D; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Zoodsma M; Department of Medical BioSciences, Radboud University Medical Center, 6500 HB, Nijmegen, the Netherlands., Claassen WJJ; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Oudakker A; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Schoenmaker C; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., Koolen DA; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., de Vries BBA; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands., 't Hoen PAC; Department of Medical BioSciences, Radboud University Medical Center, 6500 HB, Nijmegen, the Netherlands., Linda K; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands. Katrin.Linda1@radboudumc.nl., Nadif Kasri N; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands. nael.nadifkasri@radboudumc.nl. |
| Source: | Molecular psychiatry [Mol Psychiatry] 2026 Jun; Vol. 31 (6), pp. 3558-3575. Date of Electronic Publication: 2026 Feb 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41680331 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Verboven+AHA%22">Verboven AHA</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Puvogel+S%22">Puvogel S</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Latour+BL%22">Latour BL</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kolsters+N%22">Kolsters N</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lewerissa+EI%22">Lewerissa EI</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mijdam+R%22">Mijdam R</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dyke+E%22">Dyke E</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Duineveld+D%22">Duineveld D</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zoodsma+M%22">Zoodsma M</searchLink>; Department of Medical BioSciences, Radboud University Medical Center, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Claassen+WJJ%22">Claassen WJJ</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Oudakker+A%22">Oudakker A</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schoenmaker+C%22">Schoenmaker C</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Koolen+DA%22">Koolen DA</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Vries+BBA%22">de Vries BBA</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22't+Hoen+PAC%22">'t Hoen PAC</searchLink>; Department of Medical BioSciences, Radboud University Medical Center, 6500 HB, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Linda+K%22">Linda K</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands. Katrin.Linda1@radboudumc.nl.<br /><searchLink fieldCode="AU" term="%22Nadif+Kasri+N%22">Nadif Kasri N</searchLink>; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB, Nijmegen, the Netherlands. nael.nadifkasri@radboudumc.nl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Jun; Vol. 31 (6), pp. 3558-3575. <i>Date of Electronic Publication: </i>2026 Feb 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41680331 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41380-026-03482-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 3558 Titles: – TitleFull: Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Verboven AHA – PersonEntity: Name: NameFull: Puvogel S – PersonEntity: Name: NameFull: Latour BL – PersonEntity: Name: NameFull: Kolsters N – PersonEntity: Name: NameFull: Lewerissa EI – PersonEntity: Name: NameFull: Mijdam R – PersonEntity: Name: NameFull: Dyke E – PersonEntity: Name: NameFull: Duineveld D – PersonEntity: Name: NameFull: Zoodsma M – PersonEntity: Name: NameFull: Claassen WJJ – PersonEntity: Name: NameFull: Oudakker A – PersonEntity: Name: NameFull: Schoenmaker C – PersonEntity: Name: NameFull: Koolen DA – PersonEntity: Name: NameFull: de Vries BBA – PersonEntity: Name: NameFull: 't Hoen PAC – PersonEntity: Name: NameFull: Linda K – PersonEntity: Name: NameFull: Nadif Kasri N IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5578 Numbering: – Type: volume Value: 31 – Type: issue Value: 6 Titles: – TitleFull: Molecular psychiatry Type: main |
| ResultId | 1 |
