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Lay community health worker-led care with mobile decision support for uncontrolled hypertension: a cluster-randomized trial.

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Title: Lay community health worker-led care with mobile decision support for uncontrolled hypertension: a cluster-randomized trial.
Authors: Gerber F; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland. felix.gerber@usb.ch.; University of Basel, Basel, Switzerland. felix.gerber@usb.ch.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland. felix.gerber@usb.ch., Sanchez-Samaniego G; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Gupta R; SolidarMed Lesotho, Maseru, Lesotho., Lejone TI; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Tahirsylaj T; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Raeber F; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Chitja M; SolidarMed Lesotho, Maseru, Lesotho., Mathulise M; SolidarMed Lesotho, Maseru, Lesotho., Kabi T; SolidarMed Lesotho, Maseru, Lesotho., Mokaeane M; SolidarMed Lesotho, Maseru, Lesotho., Maphenchane M; SolidarMed Lesotho, Maseru, Lesotho., Molulela M; SolidarMed Lesotho, Maseru, Lesotho., Khomolishoele M; SolidarMed Lesotho, Maseru, Lesotho., Mota M; SolidarMed Lesotho, Maseru, Lesotho., Masike S; SolidarMed Lesotho, Maseru, Lesotho., Bane M; SolidarMed Lesotho, Maseru, Lesotho., Mofokeng M; SolidarMed Lesotho, Maseru, Lesotho., Sematle MP; SolidarMed Lesotho, Maseru, Lesotho., Makabateng R; SolidarMed Lesotho, Maseru, Lesotho., Mphunyane M; Ministry of Health Lesotho, Maseru, Lesotho., Sao L; Ministry of Health Lesotho, Maseru, Lesotho., Tlahali M; Ministry of Health Lesotho, Maseru, Lesotho., Litaba M; Ministry of Health Lesotho, Maseru, Lesotho., Basler DB; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Business, Economics and Informatics, University of Zurich, Zurich, Switzerland., Kindler K; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Business, Economics and Informatics, University of Zurich, Zurich, Switzerland., Ayakaka I; SolidarMed Lesotho, Maseru, Lesotho., Grimm P; SolidarMed Switzerland, Lucerne, Switzerland., Burkard T; Medical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.; Department of Cardiology, University Hospital Basel, Basel, Switzerland., Chammartin F; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Amstutz A; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, University of Oslo, Oslo, Norway.; Electronic Health Records Group, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Labhardt ND; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland. niklaus.labhardt@usb.ch.; University of Basel, Basel, Switzerland. niklaus.labhardt@usb.ch.
Source: Nature medicine [Nat Med] 2026 Mar; Vol. 32 (3), pp. 915-923. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gerber+F%22">Gerber F</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland. felix.gerber@usb.ch.; University of Basel, Basel, Switzerland. felix.gerber@usb.ch.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland. felix.gerber@usb.ch.<br /><searchLink fieldCode="AU" term="%22Sanchez-Samaniego+G%22">Sanchez-Samaniego G</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Lejone+TI%22">Lejone TI</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tahirsylaj+T%22">Tahirsylaj T</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Raeber+F%22">Raeber F</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chitja+M%22">Chitja M</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Mathulise+M%22">Mathulise M</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Kabi+T%22">Kabi T</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Mokaeane+M%22">Mokaeane M</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Maphenchane+M%22">Maphenchane M</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Molulela+M%22">Molulela M</searchLink>; 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Ministry of Health Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Tlahali+M%22">Tlahali M</searchLink>; Ministry of Health Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Litaba+M%22">Litaba M</searchLink>; Ministry of Health Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Basler+DB%22">Basler DB</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Business, Economics and Informatics, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kindler+K%22">Kindler K</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Business, Economics and Informatics, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ayakaka+I%22">Ayakaka I</searchLink>; SolidarMed Lesotho, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Grimm+P%22">Grimm P</searchLink>; SolidarMed Switzerland, Lucerne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Burkard+T%22">Burkard T</searchLink>; Medical Outpatient Department and Hypertension Centre, ESH Hypertension Centre of Excellence, University Hospital Basel, Basel, Switzerland.; Department of Cardiology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chammartin+F%22">Chammartin F</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Amstutz+A%22">Amstutz A</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, University of Oslo, Oslo, Norway.; Electronic Health Records Group, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Labhardt+ND%22">Labhardt ND</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland. niklaus.labhardt@usb.ch.; University of Basel, Basel, Switzerland. niklaus.labhardt@usb.ch.
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