View in EDS

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity.

Saved in:
Bibliographic Details
Title: Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity.
Authors: Daneshnia F; Institute of Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, Amsterdam, Netherlands.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA., Cai L; Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China.; The Center for Fungal Infectious Diseases Basic Research and Innovation of Medicine and Pharmacy, Ministry of Education, Shanghai, China., Gunasekaran D; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA., Gautam I; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA., Perry AM; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA., Mosharaf Ghahfarokhy P; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA., Ebadati A; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA., Munoz J; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA., Padilla D; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA., Hilmioglu-Polat S; Department of Medical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey., Mei S; Fralin Biomedical Research Institute, Virginia Tech FBRI21 Cancer Research Center, Washington, DC, USA.; Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, USA., Floyd DJ; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA., Schikora-Tamarit MÀ; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Fuentes D; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Artigues-Lleixà M; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Walker LA; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Gonçalves SM; School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Braga, Portugal., Salehi M; Department Industrial Engineering Faculty of K.N, KN Toosi University of Technology, Tehran, Iran., Carvalho A; School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Braga, Portugal., Desai JV; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA., Perlin DS; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.; Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.; Department of Medical Sciences, Hackensack Meridian School of Medicine, Nutley, New Jersey, USA., Munro CA; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom., Hopke A; Department of Biomedical Sciences, East Tennessee State University Quillen College of Medicine, Center of Excellence in Inflammation, Infectious Disease and Immunity, East Tennessee State University, Johnson City, Tennessee, USA., Wang T; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA., Gabaldón T; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Catalan Institution for Research and Advanced Studies, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Fang W; Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China.; The Center for Fungal Infectious Diseases Basic Research and Innovation of Medicine and Pharmacy, Ministry of Education, Shanghai, China., Nobile CJ; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA., Mansour MK; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Arastehfar A; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; University Hospital Wuerzburg, Medical Hospital II, Würzburg, Germany.
Source: Microbiology spectrum [Microbiol Spectr] 2026 Apr 07; Vol. 14 (4), pp. e0304325. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41685898
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Daneshnia+F%22">Daneshnia F</searchLink>; Institute of Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, Amsterdam, Netherlands.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Cai+L%22">Cai L</searchLink>; Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China.; The Center for Fungal Infectious Diseases Basic Research and Innovation of Medicine and Pharmacy, Ministry of Education, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Gunasekaran+D%22">Gunasekaran D</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Gautam+I%22">Gautam I</searchLink>; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Perry+AM%22">Perry AM</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Mosharaf+Ghahfarokhy+P%22">Mosharaf Ghahfarokhy P</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Ebadati+A%22">Ebadati A</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Munoz+J%22">Munoz J</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Padilla+D%22">Padilla D</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Hilmioglu-Polat+S%22">Hilmioglu-Polat S</searchLink>; Department of Medical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Mei+S%22">Mei S</searchLink>; Fralin Biomedical Research Institute, Virginia Tech FBRI21 Cancer Research Center, Washington, DC, USA.; Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Floyd+DJ%22">Floyd DJ</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Schikora-Tamarit+MÀ%22">Schikora-Tamarit MÀ</searchLink>; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fuentes+D%22">Fuentes D</searchLink>; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Artigues-Lleixà+M%22">Artigues-Lleixà M</searchLink>; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Walker+LA%22">Walker LA</searchLink>; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gonçalves+SM%22">Gonçalves SM</searchLink>; School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Braga, Portugal.<br /><searchLink fieldCode="AU" term="%22Salehi+M%22">Salehi M</searchLink>; Department Industrial Engineering Faculty of K.N, KN Toosi University of Technology, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Carvalho+A%22">Carvalho A</searchLink>; School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Guimarães, Braga, Portugal.<br /><searchLink fieldCode="AU" term="%22Desai+JV%22">Desai JV</searchLink>; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Perlin+DS%22">Perlin DS</searchLink>; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.; Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.; Department of Medical Sciences, Hackensack Meridian School of Medicine, Nutley, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Munro+CA%22">Munro CA</searchLink>; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hopke+A%22">Hopke A</searchLink>; Department of Biomedical Sciences, East Tennessee State University Quillen College of Medicine, Center of Excellence in Inflammation, Infectious Disease and Immunity, East Tennessee State University, Johnson City, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Chemistry, Michigan State University, East Lansing, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Gabaldón+T%22">Gabaldón T</searchLink>; Life Sciences Programme, Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Catalan Institution for Research and Advanced Studies, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fang+W%22">Fang W</searchLink>; Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China.; The Center for Fungal Infectious Diseases Basic Research and Innovation of Medicine and Pharmacy, Ministry of Education, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Nobile+CJ%22">Nobile CJ</searchLink>; Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA.<br /><searchLink fieldCode="AU" term="%22Mansour+MK%22">Mansour MK</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Arastehfar+A%22">Arastehfar A</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; University Hospital Wuerzburg, Medical Hospital II, Würzburg, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101634614%22">Microbiology spectrum</searchLink> [Microbiol Spectr] 2026 Apr 07; Vol. 14 (4), pp. e0304325. <i>Date of Electronic Publication: </i>2026 Feb 13.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ASM+Press%22">ASM Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101634614 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2165-0497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221650497%22">21650497 </searchLink><i>NLM ISO Abbreviation: </i>Microbiol Spectr <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41685898
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1128/spectrum.03043-25
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e0304325
    Titles:
      – TitleFull: Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Daneshnia F
      – PersonEntity:
          Name:
            NameFull: Cai L
      – PersonEntity:
          Name:
            NameFull: Gunasekaran D
      – PersonEntity:
          Name:
            NameFull: Gautam I
      – PersonEntity:
          Name:
            NameFull: Perry AM
      – PersonEntity:
          Name:
            NameFull: Mosharaf Ghahfarokhy P
      – PersonEntity:
          Name:
            NameFull: Ebadati A
      – PersonEntity:
          Name:
            NameFull: Munoz J
      – PersonEntity:
          Name:
            NameFull: Padilla D
      – PersonEntity:
          Name:
            NameFull: Hilmioglu-Polat S
      – PersonEntity:
          Name:
            NameFull: Mei S
      – PersonEntity:
          Name:
            NameFull: Floyd DJ
      – PersonEntity:
          Name:
            NameFull: Schikora-Tamarit MÀ
      – PersonEntity:
          Name:
            NameFull: Fuentes D
      – PersonEntity:
          Name:
            NameFull: Artigues-Lleixà M
      – PersonEntity:
          Name:
            NameFull: Walker LA
      – PersonEntity:
          Name:
            NameFull: Gonçalves SM
      – PersonEntity:
          Name:
            NameFull: Salehi M
      – PersonEntity:
          Name:
            NameFull: Carvalho A
      – PersonEntity:
          Name:
            NameFull: Desai JV
      – PersonEntity:
          Name:
            NameFull: Perlin DS
      – PersonEntity:
          Name:
            NameFull: Munro CA
      – PersonEntity:
          Name:
            NameFull: Hopke A
      – PersonEntity:
          Name:
            NameFull: Wang T
      – PersonEntity:
          Name:
            NameFull: Gabaldón T
      – PersonEntity:
          Name:
            NameFull: Fang W
      – PersonEntity:
          Name:
            NameFull: Nobile CJ
      – PersonEntity:
          Name:
            NameFull: Mansour MK
      – PersonEntity:
          Name:
            NameFull: Arastehfar A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 07
              M: 04
              Text: 2026 Apr 07
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2165-0497
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Microbiology spectrum
              Type: main
ResultId 1