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IFIT3 stabilizes STING via USP18 to drive M1 macrophage polarization and early inflammation in acute lung injury.

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Title: IFIT3 stabilizes STING via USP18 to drive M1 macrophage polarization and early inflammation in acute lung injury.
Authors: Tang N; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Medical Intensive Care Unit, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, China., Yang Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Zeng Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Zhu J; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Li J; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Wang J; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Ding L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China., Huang JA; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. huang_jian_an@163.com.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China. huang_jian_an@163.com., Liu Z; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. liuzeyisuda@163.com.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China. liuzeyisuda@163.com.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Feb 13; Vol. 83 (1), pp. 110. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IFIT3 stabilizes STING via USP18 to drive M1 macrophage polarization and early inflammation in acute lung injury.
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  Data: <searchLink fieldCode="AU" term="%22Tang+N%22">Tang N</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Medical Intensive Care Unit, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Zeng+Y%22">Zeng Y</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Ding+L%22">Ding L</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China.<br /><searchLink fieldCode="AU" term="%22Huang+JA%22">Huang JA</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. huang_jian_an@163.com.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China. huang_jian_an@163.com.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. liuzeyisuda@163.com.; Institute of Respiratory Diseases, Soochow University, Suzhou, 215006, China. liuzeyisuda@163.com.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Feb 13; Vol. 83 (1), pp. 110. <i>Date of Electronic Publication: </i>2026 Feb 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-025-06016-w
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        Text: English
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              Text: 2026 Feb 13
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