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Large language models provide unsafe answers to patient-posed medical questions.

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Title: Large language models provide unsafe answers to patient-posed medical questions.
Authors: Draelos RL; Glass Box Medicine, Durham, NC, USA. rachel.draelos@glassboxmedicine.com., Afreen S; University of Virginia, Charlottesville, VA, USA., Blasko B; Riverside Community Hospital, Riverside, CA, USA., Brazile TL; Inova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, VA, USA., Chase N; Cooper University Hospital, Camden, NJ, USA., Desai DP; South Texas Research Institute, Brownsville, TX, USA., Evert J; University of California, San Francisco, CA, USA., Gardner HL; Valley View Hospital, Glenwood Springs, CO, USA., Herrmann L; University of Louisville, Louisville, KY, USA., House AV; University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Kass S; Northwell Health, Manhasset, NY, USA., Kavan M; Independent Researcher, Zug, Switzerland., Khemani K; Emory University, Atlanta, GA, USA., Koire A; Brigham and Women's Hospital, Boston, MA, USA., McDonald LM; Castilleja School, Palo Alto, CA, USA., Rabeeah Z; Piedmont Healthcare, Athens, GA, USA., Shah A; AmyMD Wellness, Scottsdale, AZ, USA.
Source: NPJ digital medicine [NPJ Digit Med] 2026 Feb 13; Vol. 9 (1). Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101731738 Publication Model: Electronic Cited Medium: Internet ISSN: 2398-6352 (Electronic) Linking ISSN: 23986352 NLM ISO Abbreviation: NPJ Digit Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Large language models provide unsafe answers to patient-posed medical questions.
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  Data: <searchLink fieldCode="AU" term="%22Draelos+RL%22">Draelos RL</searchLink>; Glass Box Medicine, Durham, NC, USA. rachel.draelos@glassboxmedicine.com.<br /><searchLink fieldCode="AU" term="%22Afreen+S%22">Afreen S</searchLink>; University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Blasko+B%22">Blasko B</searchLink>; Riverside Community Hospital, Riverside, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brazile+TL%22">Brazile TL</searchLink>; Inova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, VA, USA.<br /><searchLink fieldCode="AU" term="%22Chase+N%22">Chase N</searchLink>; Cooper University Hospital, Camden, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Desai+DP%22">Desai DP</searchLink>; South Texas Research Institute, Brownsville, TX, USA.<br /><searchLink fieldCode="AU" term="%22Evert+J%22">Evert J</searchLink>; University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gardner+HL%22">Gardner HL</searchLink>; Valley View Hospital, Glenwood Springs, CO, USA.<br /><searchLink fieldCode="AU" term="%22Herrmann+L%22">Herrmann L</searchLink>; University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22House+AV%22">House AV</searchLink>; University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Kass+S%22">Kass S</searchLink>; Northwell Health, Manhasset, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kavan+M%22">Kavan M</searchLink>; Independent Researcher, Zug, Switzerland.<br /><searchLink fieldCode="AU" term="%22Khemani+K%22">Khemani K</searchLink>; Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Koire+A%22">Koire A</searchLink>; Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McDonald+LM%22">McDonald LM</searchLink>; Castilleja School, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rabeeah+Z%22">Rabeeah Z</searchLink>; Piedmont Healthcare, Athens, GA, USA.<br /><searchLink fieldCode="AU" term="%22Shah+A%22">Shah A</searchLink>; AmyMD Wellness, Scottsdale, AZ, USA.
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  Data: <searchLink fieldCode="JN" term="%22101731738%22">NPJ digital medicine</searchLink> [NPJ Digit Med] 2026 Feb 13; Vol. 9 (1). <i>Date of Electronic Publication: </i>2026 Feb 13.
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