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Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis.

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Title: Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis.
Authors: Dupuy P; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Pierre.Dupuy@ipbs.fr., Boudehen YM; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Bacterial Cell Cycle Mechanisms Unit, F-75015, Paris, France., Faucher M; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; G.CLIPS BIOTECH, Labège, France., Buglino JA; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA., Fay A; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA., Cantaloube S; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France., Grimoire Y; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France., Marcoux J; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Infrastructure Nationale de Protéomique, ProFI, UAR 2048, Toulouse, France., Levet F; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France.; Univ. Bordeaux, CNRS, INSERM, Bordeaux Imaging Center, BIC, UAR3420, US 4, F-33000, Bordeaux, France., Bettarel L; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France., Voisin B; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France., Rech J; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France., Bouet JY; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France., Saurel O; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France., Sibarita JB; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France., Glickman M; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA., Gutierrez C; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France., Neyrolles O; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Olivier.Neyrolles@ipbs.fr.
Source: The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (7), pp. 2306-2337. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis.
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  Data: <searchLink fieldCode="AU" term="%22Dupuy+P%22">Dupuy P</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Pierre.Dupuy@ipbs.fr.<br /><searchLink fieldCode="AU" term="%22Boudehen+YM%22">Boudehen YM</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Bacterial Cell Cycle Mechanisms Unit, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Faucher+M%22">Faucher M</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; G.CLIPS BIOTECH, Labège, France.<br /><searchLink fieldCode="AU" term="%22Buglino+JA%22">Buglino JA</searchLink>; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Fay+A%22">Fay A</searchLink>; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Cantaloube+S%22">Cantaloube S</searchLink>; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Grimoire+Y%22">Grimoire Y</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Marcoux+J%22">Marcoux J</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Infrastructure Nationale de Protéomique, ProFI, UAR 2048, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Levet+F%22">Levet F</searchLink>; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France.; Univ. Bordeaux, CNRS, INSERM, Bordeaux Imaging Center, BIC, UAR3420, US 4, F-33000, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Bettarel+L%22">Bettarel L</searchLink>; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Voisin+B%22">Voisin B</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Rech+J%22">Rech J</searchLink>; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bouet+JY%22">Bouet JY</searchLink>; Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Saurel+O%22">Saurel O</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Sibarita+JB%22">Sibarita JB</searchLink>; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Glickman+M%22">Glickman M</searchLink>; Immunology Program, Sloan Kettering Institute, New-York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+C%22">Gutierrez C</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Neyrolles+O%22">Neyrolles O</searchLink>; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Olivier.Neyrolles@ipbs.fr.
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