Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells.
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| Title: | Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells. |
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| Authors: | Yang YF; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Chang YC; Department of Biomedical Imaging and Radiological Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chan MH; Department of Biomedical Imaging and Radiological Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lin MH; Division of Chest Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Yang CJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Huang MS; School of Medicine, I-Shou University, Kaohsiung, Taiwan., Jan YH; Department of Molecular Medicine, Koo Foundation Sun Yat-Sen Cancer Center, 125 Lih-Der Road, Pei-Tou District, Taipei City, 12259, Taiwan. isaacjan@kfsyscc.org.; Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei, 115201, Taiwan. isaacjan@kfsyscc.org., Hsiao M; Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei, 115201, Taiwan. mhsiao@gate.sinica.edu.tw.; Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan. mhsiao@gate.sinica.edu.tw. |
| Source: | Cancer cell international [Cancer Cell Int] 2026 Feb 13; Vol. 26 (1). Date of Electronic Publication: 2026 Feb 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101139795 Publication Model: Electronic Cited Medium: Print ISSN: 1475-2867 (Print) Linking ISSN: 14752867 NLM ISO Abbreviation: Cancer Cell Int Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41689001 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yang+YF%22">Yang YF</searchLink>; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+YC%22">Chang YC</searchLink>; Department of Biomedical Imaging and Radiological Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chan+MH%22">Chan MH</searchLink>; Department of Biomedical Imaging and Radiological Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+MH%22">Lin MH</searchLink>; Division of Chest Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+CJ%22">Yang CJ</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+MS%22">Huang MS</searchLink>; School of Medicine, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jan+YH%22">Jan YH</searchLink>; Department of Molecular Medicine, Koo Foundation Sun Yat-Sen Cancer Center, 125 Lih-Der Road, Pei-Tou District, Taipei City, 12259, Taiwan. isaacjan@kfsyscc.org.; Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei, 115201, Taiwan. isaacjan@kfsyscc.org.<br /><searchLink fieldCode="AU" term="%22Hsiao+M%22">Hsiao M</searchLink>; Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei, 115201, Taiwan. mhsiao@gate.sinica.edu.tw.; Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan. mhsiao@gate.sinica.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101139795%22">Cancer cell international</searchLink> [Cancer Cell Int] 2026 Feb 13; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Feb 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101139795 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1475-2867 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214752867%22">14752867 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Cell Int <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41689001 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12935-026-04220-7 Languages: – Code: eng Text: English Titles: – TitleFull: Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yang YF – PersonEntity: Name: NameFull: Chang YC – PersonEntity: Name: NameFull: Chan MH – PersonEntity: Name: NameFull: Lin MH – PersonEntity: Name: NameFull: Yang CJ – PersonEntity: Name: NameFull: Huang MS – PersonEntity: Name: NameFull: Jan YH – PersonEntity: Name: NameFull: Hsiao M IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 02 Text: 2026 Feb 13 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1475-2867 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: Cancer cell international Type: main |
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