Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial.

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Title: Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial.
Authors: Fernández-Martínez A; Faculty of Medicine, University of the Basque Country, Leioa, Bizkaia, Spain; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain. Electronic address: afernandez450@ikasle.ehu.eus., López Picado A; Department of Public Health and Preventive Medicine, University of the Basque Country, Bilbao, Spain., González-García J; Department of Surgery, Radiology and Physical Medicine, University of the Basque Country, Bilbao, Spain; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario de Basurto, Bilbao, Spain., Aguado Sevilla M; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Lobato Solores F; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Castroviejo Ibáñez B; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., de Miguel Fernández P; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Benito Martínez P; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Valero González S; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Galve Marqués AI; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain., Mainar Gil I; Intensive Care Medicine, Hospital Universitario San Pedro, Logroño, Spain., Boukichou Abdelkader N; Department of Statistics, Data Science Unit, La Rioja Biomedical Research Center (CIBIR), Logroño, Spain., Íñiguez Martínez M; Department of Infectious Diseases, La Rioja Biomedical Research Center (CIBIR), Logroño, Spain., Bermejo Bravo A; Hospital Pharmacy, Hospital Universitario San Pedro, Logroño, Spain., Apiñaniz Apiñaniz R; Hospital Pharmacy, Hospital Universitario San Pedro, Logroño, Spain., Corral Cárdenas E; Hospital Universitario San Pedro, Logroño, Spain., Ferreira Laso L; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.
Source: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2026 Jun; Vol. 40 (6), pp. 1668-1677. Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8422 (Electronic) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Fernández-Martínez+A%22">Fernández-Martínez A</searchLink>; Faculty of Medicine, University of the Basque Country, Leioa, Bizkaia, Spain; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain. Electronic address: afernandez450@ikasle.ehu.eus.<br /><searchLink fieldCode="AU" term="%22López+Picado+A%22">López Picado A</searchLink>; Department of Public Health and Preventive Medicine, University of the Basque Country, Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22González-García+J%22">González-García J</searchLink>; Department of Surgery, Radiology and Physical Medicine, University of the Basque Country, Bilbao, Spain; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario de Basurto, Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22Aguado+Sevilla+M%22">Aguado Sevilla M</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Lobato+Solores+F%22">Lobato Solores F</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Castroviejo+Ibáñez+B%22">Castroviejo Ibáñez B</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22de+Miguel+Fernández+P%22">de Miguel Fernández P</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Benito+Martínez+P%22">Benito Martínez P</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Valero+González+S%22">Valero González S</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Galve+Marqués+AI%22">Galve Marqués AI</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Mainar+Gil+I%22">Mainar Gil I</searchLink>; Intensive Care Medicine, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Boukichou+Abdelkader+N%22">Boukichou Abdelkader N</searchLink>; Department of Statistics, Data Science Unit, La Rioja Biomedical Research Center (CIBIR), Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Íñiguez+Martínez+M%22">Íñiguez Martínez M</searchLink>; Department of Infectious Diseases, La Rioja Biomedical Research Center (CIBIR), Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Bermejo+Bravo+A%22">Bermejo Bravo A</searchLink>; Hospital Pharmacy, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Apiñaniz+Apiñaniz+R%22">Apiñaniz Apiñaniz R</searchLink>; Hospital Pharmacy, Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Corral+Cárdenas+E%22">Corral Cárdenas E</searchLink>; Hospital Universitario San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Ferreira+Laso+L%22">Ferreira Laso L</searchLink>; Anaesthesiology, Resuscitation and Pain Management, Hospital Universitario San Pedro, Logroño, Spain.
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  Data: <searchLink fieldCode="JN" term="%229110208%22">Journal of cardiothoracic and vascular anesthesia</searchLink> [J Cardiothorac Vasc Anesth] 2026 Jun; Vol. 40 (6), pp. 1668-1677. <i>Date of Electronic Publication: </i>2026 Jan 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9110208 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-8422 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210530770%22">10530770 </searchLink><i>NLM ISO Abbreviation: </i>J Cardiothorac Vasc Anesth <i>Subsets: </i>MEDLINE
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        Value: 10.1053/j.jvca.2026.01.008
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        Text: English
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              Text: 2026 Jun
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