Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents.
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| Title: | Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents. |
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| Authors: | Moradimehrabadi M; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Khabnadideh S; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.; Pharmaceutical Sciences Research Center, Faculty of pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Emami L; Pharmaceutical Sciences Research Center, Faculty of pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Mostashfi H; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Khajehpour N; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Firozbakhsh M; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran., Sadeghian S; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. s_sadeghian@sums.ac.ir., Rezaei Z; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. rezaeiza@sums.ac.ir. |
| Source: | BMC chemistry [BMC Chem] 2026 Feb 14; Vol. 20 (1). Date of Electronic Publication: 2026 Feb 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 101741142 Publication Model: Electronic Cited Medium: Internet ISSN: 2661-801X (Electronic) Linking ISSN: 2661801X NLM ISO Abbreviation: BMC Chem Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41691293 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Moradimehrabadi+M%22">Moradimehrabadi M</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Khabnadideh+S%22">Khabnadideh S</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.; Pharmaceutical Sciences Research Center, Faculty of pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Emami+L%22">Emami L</searchLink>; Pharmaceutical Sciences Research Center, Faculty of pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Mostashfi+H%22">Mostashfi H</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Khajehpour+N%22">Khajehpour N</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Firozbakhsh+M%22">Firozbakhsh M</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.<br /><searchLink fieldCode="AU" term="%22Sadeghian+S%22">Sadeghian S</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. s&#95;sadeghian@sums.ac.ir.<br /><searchLink fieldCode="AU" term="%22Rezaei+Z%22">Rezaei Z</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. rezaeiza@sums.ac.ir. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101741142%22">BMC chemistry</searchLink> [BMC Chem] 2026 Feb 14; Vol. 20 (1). <i>Date of Electronic Publication: </i>2026 Feb 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101741142 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2661-801X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222661801X%22">2661801X </searchLink><i>NLM ISO Abbreviation: </i>BMC Chem <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41691293 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13065-026-01744-x Languages: – Code: eng Text: English Titles: – TitleFull: Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moradimehrabadi M – PersonEntity: Name: NameFull: Khabnadideh S – PersonEntity: Name: NameFull: Emami L – PersonEntity: Name: NameFull: Mostashfi H – PersonEntity: Name: NameFull: Khajehpour N – PersonEntity: Name: NameFull: Firozbakhsh M – PersonEntity: Name: NameFull: Sadeghian S – PersonEntity: Name: NameFull: Rezaei Z IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 02 Text: 2026 Feb 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2661-801X Numbering: – Type: volume Value: 20 – Type: issue Value: 1 Titles: – TitleFull: BMC chemistry Type: main |
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