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FKBP10 promotes M2 polarization of macrophage via MEK/ERK/CXCL8 axis and facilitates tumor progression in clear cell renal cell carcinoma.

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Title: FKBP10 promotes M2 polarization of macrophage via MEK/ERK/CXCL8 axis and facilitates tumor progression in clear cell renal cell carcinoma.
Authors: Chen JW; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Li JY; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Feng HQ; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Fu LM; Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Disease, Changsha, Hunan, China., Zhou XW; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Lin HS; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Wang YH; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Liu KZ; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Chen YH; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Wang Z; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China., Deng Q; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China., Wang JY; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China., Jin MY; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China., Liang H; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China., Wei JH; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Luo JH; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Gui CP; Department of Urology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Source: International journal of biological sciences [Int J Biol Sci] 2026 Jan 15; Vol. 22 (4), pp. 1807-1833. Date of Electronic Publication: 2026 Jan 15 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FKBP10 promotes M2 polarization of macrophage via MEK/ERK/CXCL8 axis and facilitates tumor progression in clear cell renal cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Chen+JW%22">Chen JW</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+JY%22">Li JY</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Feng+HQ%22">Feng HQ</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Fu+LM%22">Fu LM</searchLink>; Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Disease, Changsha, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Zhou+XW%22">Zhou XW</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lin+HS%22">Lin HS</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wang+YH%22">Wang YH</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+KZ%22">Liu KZ</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Deng+Q%22">Deng Q</searchLink>; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wang+JY%22">Wang JY</searchLink>; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Jin+MY%22">Jin MY</searchLink>; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liang+H%22">Liang H</searchLink>; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wei+JH%22">Wei JH</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Luo+JH%22">Luo JH</searchLink>; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Gui+CP%22">Gui CP</searchLink>; Department of Urology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2026 Jan 15; Vol. 22 (4), pp. 1807-1833. <i>Date of Electronic Publication: </i>2026 Jan 15 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International%22">Ivyspring International </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101235568 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1449-2288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214492288%22">14492288 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Sci <i>Subsets: </i>MEDLINE
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