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Changes in Demographics, Initial Treatment Strategies, and Clinical Outcomes of Severe Aortic Stenosis in the Pre- and Post-TAVR Era in Japan.

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Title: Changes in Demographics, Initial Treatment Strategies, and Clinical Outcomes of Severe Aortic Stenosis in the Pre- and Post-TAVR Era in Japan.
Authors: Takeji Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Kanazawa University, Japan (Y.T.).; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Taniguchi T; Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Taniguchi, T. Kitai, R.M.)., Morimoto T; Department of Data Science, Hyogo Medical University, Nishinomiya, Japan (T.M., Y.Y.)., Shirai S; Division of Cardiology (S.S., H. Tabata, K.Y., K.A.), Kokura Memorial Hospital, Kitakyushu, Japan., Kitai T; Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Taniguchi, T. Kitai, R.M.).; Department of Heart Failure and Transplantation (T. Kitai, M.A.), National Cerebral and Cardiovascular Center, Suita, Japan., Tabata H; Division of Cardiology (S.S., H. Tabata, K.Y., K.A.), Kokura Memorial Hospital, Kitakyushu, Japan., Ohno N; Division of Cardiovascular Surgery (N.O.), Kokura Memorial Hospital, Kitakyushu, Japan., Murai R; Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Taniguchi, T. Kitai, R.M.)., Osakada K; Department of Cardiology (K. Osakada), Kurashiki Central Hospital, Japan., Murata K; Department of Cardiology (K. Murata), Shizuoka City Shizuoka Hospital, Japan., Nakai M; Department of Cardiovascular Surgery (M.N.), Shizuoka City Shizuoka Hospital, Japan.; Department of Cardiology, Koto Memorial Hospital, Higashiomi, Japan (M.K.)., Tsuneyoshi H; Department of Cardiovascular Surgery (H. Tsuneyoshi), Shizuoka General Hospital, Japan., Tada T; Department of Cardiology (T. Tada), Shizuoka General Hospital, Japan., Amano M; Department of Heart Failure and Transplantation (T. Kitai, M.A.), National Cerebral and Cardiovascular Center, Suita, Japan., Watanabe S; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Shiomi H; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Watanabe H; Department of Cardiology, Hirakata Kohsai Hospital, Japan (H.W., T. Kimura)., Yoshikawa Y; Department of Data Science, Hyogo Medical University, Nishinomiya, Japan (T.M., Y.Y.).; Department of Biostatistics (Y.Y.), National Cerebral and Cardiovascular Center, Suita, Japan., Nishikawa R; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Obayashi Y; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Yamamoto K; Division of Cardiology (S.S., H. Tabata, K.Y., K.A.), Kokura Memorial Hospital, Kitakyushu, Japan., Toyofuku M; Department of Cardiology, Japanese Red Cross Wakayama Medical Center (M.T., S.T., T.F.)., Tatsushima S; Department of Cardiology, Japanese Red Cross Wakayama Medical Center (M.T., S.T., T.F.)., Kanamori N; Division of Cardiology, Shimada General Medical Center, Japan (N.K.)., Miyake M; Department of Cardiology, Tenri Hospital, Japan (M.M.)., Nakayama H; Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Japan (H.N.)., Nagao K; Department of Cardiovascular Center, Osaka Red Cross Hospital, Japan (K. Nagao)., Izuhara M; Department of Cardiology, Kishiwada City Hospital, Japan (I.M.)., Nakatsuma K; Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan (K. Nakatsuma)., Inoko M; Department of Cardiology, Kishiwada City Hospital, Japan (I.M.).; Cardiovascular Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan (M. Inoko)., Fujita T; Department of Cardiology, Japanese Red Cross Wakayama Medical Center (M.T., S.T., T.F.)., Masahiro K; Department of Cardiology, Koto Memorial Hospital, Higashiomi, Japan (M.K.)., Ishii M; Department of Cardiology, National Hospital Organization Kyoto Medical Center, Japan (M. Ishii)., Usami S; Department of Cardiology, Kansai Electric Power Hospital, Osaka, Japan (S.U.)., Nakazeki F; Department of Cardiology, Japanese Red Cross Otsu Hospital (F.N.)., Inuzuka Y; Department of Cardiology, Shiga General Hospital, Moriyama, Japan (Y.I.)., Ando K; Division of Cardiology (S.S., H. Tabata, K.Y., K.A.), Kokura Memorial Hospital, Kitakyushu, Japan., Komiya T; Department of Cardiovascular Surgery (T. Komiya), Kurashiki Central Hospital, Japan., Ono K; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan., Minatoya K; Department of Cardiovascular Surgery (K. Minatoya), Graduate School of Medicine, Kyoto University, Japan., Kimura T; Department of Cardiology, Hirakata Kohsai Hospital, Japan (H.W., T. Kimura).
Corporate Authors: CURRENT AS Registry-2 Investigators
Source: Circulation. Population health and outcomes [Circ Popul Health Outcomes] 2026 Feb; Vol. 19 (2), pp. e012639. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 9919227857106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3068-563X (Electronic) Linking ISSN: 3068563X NLM ISO Abbreviation: Circ Popul Health Outcomes Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Changes in Demographics, Initial Treatment Strategies, and Clinical Outcomes of Severe Aortic Stenosis in the Pre- and Post-TAVR Era in Japan.
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  Data: <searchLink fieldCode="AU" term="%22Takeji+Y%22">Takeji Y</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medicine, Kanazawa University, Japan (Y.T.).; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan.<br /><searchLink fieldCode="AU" term="%22Taniguchi+T%22">Taniguchi T</searchLink>; Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Taniguchi, T. Kitai, R.M.).<br /><searchLink fieldCode="AU" term="%22Morimoto+T%22">Morimoto T</searchLink>; Department of Data Science, Hyogo Medical University, Nishinomiya, Japan (T.M., Y.Y.).<br /><searchLink fieldCode="AU" term="%22Shirai+S%22">Shirai S</searchLink>; Division of Cardiology (S.S., H. 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Tada), Shizuoka General Hospital, Japan.<br /><searchLink fieldCode="AU" term="%22Amano+M%22">Amano M</searchLink>; Department of Heart Failure and Transplantation (T. Kitai, M.A.), National Cerebral and Cardiovascular Center, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+S%22">Watanabe S</searchLink>; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan.<br /><searchLink fieldCode="AU" term="%22Shiomi+H%22">Shiomi H</searchLink>; Department of Cardiovascular Medicine (Y.T., K. Ono, S.W., H.S., R.N., Y.O.), Graduate School of Medicine, Kyoto University, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+H%22">Watanabe H</searchLink>; Department of Cardiology, Hirakata Kohsai Hospital, Japan (H.W., T. 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Tabata, K.Y., K.A.), Kokura Memorial Hospital, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Toyofuku+M%22">Toyofuku M</searchLink>; Department of Cardiology, Japanese Red Cross Wakayama Medical Center (M.T., S.T., T.F.).<br /><searchLink fieldCode="AU" term="%22Tatsushima+S%22">Tatsushima S</searchLink>; Department of Cardiology, Japanese Red Cross Wakayama Medical Center (M.T., S.T., T.F.).<br /><searchLink fieldCode="AU" term="%22Kanamori+N%22">Kanamori N</searchLink>; Division of Cardiology, Shimada General Medical Center, Japan (N.K.).<br /><searchLink fieldCode="AU" term="%22Miyake+M%22">Miyake M</searchLink>; Department of Cardiology, Tenri Hospital, Japan (M.M.).<br /><searchLink fieldCode="AU" term="%22Nakayama+H%22">Nakayama H</searchLink>; Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Japan (H.N.).<br /><searchLink fieldCode="AU" term="%22Nagao+K%22">Nagao K</searchLink>; Department of Cardiovascular Center, Osaka Red Cross Hospital, Japan (K. Nagao).<br /><searchLink fieldCode="AU" term="%22Izuhara+M%22">Izuhara M</searchLink>; Department of Cardiology, Kishiwada City Hospital, Japan (I.M.).<br /><searchLink fieldCode="AU" term="%22Nakatsuma+K%22">Nakatsuma K</searchLink>; Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan (K. Nakatsuma).<br /><searchLink fieldCode="AU" term="%22Inoko+M%22">Inoko M</searchLink>; Department of Cardiology, Kishiwada City Hospital, Japan (I.M.).; Cardiovascular Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan (M. 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