Characterization and targeting of deleterious mutations in Carbapenemase-producing Klebsiella pneumoniae: insights from variant calling, Computer-aided drug design, and DFT analysis.
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| Title: | Characterization and targeting of deleterious mutations in Carbapenemase-producing Klebsiella pneumoniae: insights from variant calling, Computer-aided drug design, and DFT analysis. |
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| Authors: | Joshi T; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India., Mathpal S; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India., Kumar H; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India., Ramaiah S; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India., Anbarasu A; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India. aanand@vit.ac.in.; Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India. aanand@vit.ac.in. |
| Source: | Archives of microbiology [Arch Microbiol] 2026 Feb 16; Vol. 208 (4), pp. 193. Date of Electronic Publication: 2026 Feb 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0410427 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-072X (Electronic) Linking ISSN: 03028933 NLM ISO Abbreviation: Arch Microbiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41697402 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Characterization and targeting of deleterious mutations in Carbapenemase-producing Klebsiella pneumoniae: insights from variant calling, Computer-aided drug design, and DFT analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Joshi+T%22">Joshi T</searchLink>; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Mathpal+S%22">Mathpal S</searchLink>; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Kumar+H%22">Kumar H</searchLink>; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Ramaiah+S%22">Ramaiah S</searchLink>; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.; Department of Bio-Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Anbarasu+A%22">Anbarasu A</searchLink>; Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India. aanand@vit.ac.in.; Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, 632014, Tamil Nadu, India. aanand@vit.ac.in. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220410427%22">Archives of microbiology</searchLink> [Arch Microbiol] 2026 Feb 16; Vol. 208 (4), pp. 193. <i>Date of Electronic Publication: </i>2026 Feb 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0410427 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-072X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203028933%22">03028933 </searchLink><i>NLM ISO Abbreviation: </i>Arch Microbiol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41697402 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00203-026-04743-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 193 Titles: – TitleFull: Characterization and targeting of deleterious mutations in Carbapenemase-producing Klebsiella pneumoniae: insights from variant calling, Computer-aided drug design, and DFT analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Joshi T – PersonEntity: Name: NameFull: Mathpal S – PersonEntity: Name: NameFull: Kumar H – PersonEntity: Name: NameFull: Ramaiah S – PersonEntity: Name: NameFull: Anbarasu A IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 02 Text: 2026 Feb 16 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1432-072X Numbering: – Type: volume Value: 208 – Type: issue Value: 4 Titles: – TitleFull: Archives of microbiology Type: main |
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