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Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients.

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Title: Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients.
Authors: Aubert O; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France. Electronic address: olivier.aubert@aphp.fr., Kergaravat C; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France., Katerinis I; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Boudhabhay I; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Leon J; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Troger A; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Chavarot N; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Roger C; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Burger C; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Le Stang MB; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Sberro-Soussan R; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Amrouche L; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Martinez F; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Peraldi MN; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Legendre C; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Kaminski H; Department of Nephrology, Transplantation, Dialysis and Apheresis, Bordeaux University Hospital, Bordeaux, France; Bordeaux University, CNRS, ImmunoConcEpT UMR_5164, INSERM ERL U1303, Paris, Région île de France, France., Anglicheau D; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Scemla A; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France., Clave E; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France., Toubert A; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France; Laboratoire d'Immunologie et d'Histocompatibilité, Hôpital Saint-Louis, AP-HP, Paris, France., Zuber J; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France. Electronic address: Julien.zuber@aphp.fr.
Source: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2026 Jul; Vol. 26 (7), pp. 1703-1713. Date of Electronic Publication: 2026 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients.
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  Data: <searchLink fieldCode="AU" term="%22Aubert+O%22">Aubert O</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France. Electronic address: olivier.aubert@aphp.fr.<br /><searchLink fieldCode="AU" term="%22Kergaravat+C%22">Kergaravat C</searchLink>; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France.<br /><searchLink fieldCode="AU" term="%22Katerinis+I%22">Katerinis I</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Boudhabhay+I%22">Boudhabhay I</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Leon+J%22">Leon J</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Troger+A%22">Troger A</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Chavarot+N%22">Chavarot N</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Roger+C%22">Roger C</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Burger+C%22">Burger C</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Le+Stang+MB%22">Le Stang MB</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Sberro-Soussan+R%22">Sberro-Soussan R</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Amrouche+L%22">Amrouche L</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Martinez+F%22">Martinez F</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Peraldi+MN%22">Peraldi MN</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Legendre+C%22">Legendre C</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Kaminski+H%22">Kaminski H</searchLink>; Department of Nephrology, Transplantation, Dialysis and Apheresis, Bordeaux University Hospital, Bordeaux, France; Bordeaux University, CNRS, ImmunoConcEpT UMR_5164, INSERM ERL U1303, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Anglicheau+D%22">Anglicheau D</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Scemla+A%22">Scemla A</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France.<br /><searchLink fieldCode="AU" term="%22Clave+E%22">Clave E</searchLink>; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France.<br /><searchLink fieldCode="AU" term="%22Toubert+A%22">Toubert A</searchLink>; Université Paris Cité, Institut de Recherche Saint Louis, INSERM UMRS 1342, Paris, France; Laboratoire d'Immunologie et d'Histocompatibilité, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zuber+J%22">Zuber J</searchLink>; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; Université Paris Cité, Institut national de la santé et de la recherche médicale U1151, Centre national de la recherche scientifique Unités mixtes de recherche 8253, Institut Necker Enfants Malades, Paris, France; Fédération Hospitalo-Universitaire Transvir, Paris, Région île de France, France. Electronic address: Julien.zuber@aphp.fr.
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