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Association of early vedolizumab trough levels with clinical, biochemical, endoscopic response and drug optimization during maintenance therapy in patients with inflammatory bowel diseases.

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Title: Association of early vedolizumab trough levels with clinical, biochemical, endoscopic response and drug optimization during maintenance therapy in patients with inflammatory bowel diseases.
Authors: Kim K; Department of Gastroenterology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea., Yoon AR; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Oh K; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Hong HS; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Lee JY; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Hong SW; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Hwang SW; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Park SH; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Yang DH; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Byeon JS; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Myung SJ; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Ye BD; Department of Gastroenterology and Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea. bdye@amc.seoul.kr.
Source: Scientific reports [Sci Rep] 2026 Feb 16; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Association of early vedolizumab trough levels with clinical, biochemical, endoscopic response and drug optimization during maintenance therapy in patients with inflammatory bowel diseases.
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  Data: <searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Department of Gastroenterology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+AR%22">Yoon AR</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Oh+K%22">Oh K</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Hong+HS%22">Hong HS</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Hong+SW%22">Hong SW</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+SW%22">Hwang SW</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Park+SH%22">Park SH</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yang+DH%22">Yang DH</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Byeon+JS%22">Byeon JS</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Myung+SJ%22">Myung SJ</searchLink>; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Ye+BD%22">Ye BD</searchLink>; Department of Gastroenterology and Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea. bdye@amc.seoul.kr.
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