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Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop.

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Title: Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop.
Authors: Gant TW; Centre for Radiation, Chemical and Environmental Hazards, Toxicology Department, UK Health Security Agency, Harwell Science Campus, Didcot, OX11 0RQ, UK. tim.gant@ukhsa.gov.uk.; School of Public Health, Imperial College, London, UK. tim.gant@ukhsa.gov.uk., Boxall A; Department of Environment and Geography, University of York, York, UK., Burgwinkel D; Edelweiss Connect GmbH, Basel, CH, Switzerland., Zare Jeddi M; Shell Global Solutions International B.V, The Hague, Netherlands., Djidrovski I; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands., Friedrichs S; AcumenIST SRL, Brussels, Belgium., Hardy B; Edelweiss Connect GmbH, Basel, CH, Switzerland., Hartung T; Center for Alternatives to Animal Testing (CAAT), Doerenkam-Zbinden-Chair for Evidence-Based Toxicology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, US.; University of Konstanz, CAAT Europe, Konstanz, Germany., Holland D; ExxonMobil Petroleum and Chemical BV, Machelen, Belgium., Karwath A; College of Medicine and Health, School of Medical Sciences, University of Birmingham, Birmingham, UK., Kienhuis A; Department of Innovative Testing Strategies, Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands.; Facutly of Veterinary Medicine, Department of Population Health Sciences, Insitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands., Kleinstreuer N; Office of the Director (OD), Division of Program Coordination, Planning, and Strategic Initiatives, National Institutes of Health (NIH), Maryland, US., Lin Z; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.; Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, US., Marczylo EL; Luxembourg Institute of Science and Technology (LIST), Esch Sur Alzette, Luxembourg., Marvuglia A; Luxembourg Institute of Science and Technology (LIST), Esch Sur Alzette, Luxembourg., Qian H; ExxonMobil Biomedical Sciences, Inc, Spring, TX, US., van Ravenzwaay B; Division of Toxicology, Wageningen University, Wageningen, Netherlands., Rees P; Department of Biomedical Engineering, Swansea University, Bay Campus, Swansea, SA18EN, UK., Sarimveis H; School of Chemical Engineering, National Technical University of Athens, Athens, Greece., Tralau T; German Federal Institute for Risk Assessment (BfR), Berlin, Germany., Wilmot L; ECETOC, Rue Belliard 40, 1040 Bruxelles, Belgium., Zalewski A; Pharmaceuticals, Preclinical Development, Bayer Research & Development, Berlin, Germany., Rouquié D; Bayer SAS, Bayer Crop Science, Sophia-Antipolis, France.
Source: Archives of toxicology [Arch Toxicol] 2026 May; Vol. 100 (5), pp. 2149-2167. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gant+TW%22">Gant TW</searchLink>; Centre for Radiation, Chemical and Environmental Hazards, Toxicology Department, UK Health Security Agency, Harwell Science Campus, Didcot, OX11 0RQ, UK. tim.gant@ukhsa.gov.uk.; School of Public Health, Imperial College, London, UK. tim.gant@ukhsa.gov.uk.<br /><searchLink fieldCode="AU" term="%22Boxall+A%22">Boxall A</searchLink>; Department of Environment and Geography, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Burgwinkel+D%22">Burgwinkel D</searchLink>; Edelweiss Connect GmbH, Basel, CH, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zare+Jeddi+M%22">Zare Jeddi M</searchLink>; Shell Global Solutions International B.V, The Hague, Netherlands.<br /><searchLink fieldCode="AU" term="%22Djidrovski+I%22">Djidrovski I</searchLink>; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Friedrichs+S%22">Friedrichs S</searchLink>; AcumenIST SRL, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Hardy+B%22">Hardy B</searchLink>; Edelweiss Connect GmbH, Basel, CH, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hartung+T%22">Hartung T</searchLink>; Center for Alternatives to Animal Testing (CAAT), Doerenkam-Zbinden-Chair for Evidence-Based Toxicology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, US.; University of Konstanz, CAAT Europe, Konstanz, Germany.<br /><searchLink fieldCode="AU" term="%22Holland+D%22">Holland D</searchLink>; ExxonMobil Petroleum and Chemical BV, Machelen, Belgium.<br /><searchLink fieldCode="AU" term="%22Karwath+A%22">Karwath A</searchLink>; College of Medicine and Health, School of Medical Sciences, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Kienhuis+A%22">Kienhuis A</searchLink>; Department of Innovative Testing Strategies, Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands.; Facutly of Veterinary Medicine, Department of Population Health Sciences, Insitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kleinstreuer+N%22">Kleinstreuer N</searchLink>; Office of the Director (OD), Division of Program Coordination, Planning, and Strategic Initiatives, National Institutes of Health (NIH), Maryland, US.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.; Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, US.<br /><searchLink fieldCode="AU" term="%22Marczylo+EL%22">Marczylo EL</searchLink>; Luxembourg Institute of Science and Technology (LIST), Esch Sur Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Marvuglia+A%22">Marvuglia A</searchLink>; Luxembourg Institute of Science and Technology (LIST), Esch Sur Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Qian+H%22">Qian H</searchLink>; ExxonMobil Biomedical Sciences, Inc, Spring, TX, US.<br /><searchLink fieldCode="AU" term="%22van+Ravenzwaay+B%22">van Ravenzwaay B</searchLink>; Division of Toxicology, Wageningen University, Wageningen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Rees+P%22">Rees P</searchLink>; Department of Biomedical Engineering, Swansea University, Bay Campus, Swansea, SA18EN, UK.<br /><searchLink fieldCode="AU" term="%22Sarimveis+H%22">Sarimveis H</searchLink>; School of Chemical Engineering, National Technical University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tralau+T%22">Tralau T</searchLink>; German Federal Institute for Risk Assessment (BfR), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wilmot+L%22">Wilmot L</searchLink>; ECETOC, Rue Belliard 40, 1040 Bruxelles, Belgium.<br /><searchLink fieldCode="AU" term="%22Zalewski+A%22">Zalewski A</searchLink>; Pharmaceuticals, Preclinical Development, Bayer Research & Development, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Rouquié+D%22">Rouquié D</searchLink>; Bayer SAS, Bayer Crop Science, Sophia-Antipolis, France.
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