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Repeated moderate hypothermia leads to sustained glymphatic dysfunction and loss of vascular AQP4 polarization.

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Title: Repeated moderate hypothermia leads to sustained glymphatic dysfunction and loss of vascular AQP4 polarization.
Authors: Liu C; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Liu N; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Shanbhag NC; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Kritsilis M; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Bèchet NB; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Jukkola J; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Eltanahy AM; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.; Egyptian Medical Board, Ministry of Health and Population, Giza, Egypt., Battistella R; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Lundgaard I; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden. iben.lundgaard@med.lu.se.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden. iben.lundgaard@med.lu.se.
Source: Fluids and barriers of the CNS [Fluids Barriers CNS] 2026 Feb 16; Vol. 23 (1). Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Repeated moderate hypothermia leads to sustained glymphatic dysfunction and loss of vascular AQP4 polarization.
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  Data: <searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Shanbhag+NC%22">Shanbhag NC</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Kritsilis+M%22">Kritsilis M</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Bèchet+NB%22">Bèchet NB</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jukkola+J%22">Jukkola J</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Eltanahy+AM%22">Eltanahy AM</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.; Egyptian Medical Board, Ministry of Health and Population, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Battistella+R%22">Battistella R</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Lundgaard+I%22">Lundgaard I</searchLink>; Department of Experimental Medical Science, Lund University, Lund, 223 62, Sweden. iben.lundgaard@med.lu.se.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden. iben.lundgaard@med.lu.se.
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  Data: <searchLink fieldCode="JN" term="%22101553157%22">Fluids and barriers of the CNS</searchLink> [Fluids Barriers CNS] 2026 Feb 16; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Feb 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101553157 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-8118 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220458118%22">20458118 </searchLink><i>NLM ISO Abbreviation: </i>Fluids Barriers CNS <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12987-026-00770-0
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        Text: English
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              Text: 2026 Feb 16
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